山东省血液中心血液检测不合格情况分析

目的了解山东省血液中心无偿献血者实验室检测不合格情况,为进一步 提高无偿献血资源利用率提供参考。方法回顾性分析2016年1月至2018年12月山东省血液中心对献血人群检测不合格的资料.按模式不同分为快速检测和实验室检测,分析不合格项目的数据。结果献血前快速检测312 780人次,不合格率为5.67%(17 736/312 780);实验室检测不合格率为1.35%(3942291 799) ,呈逐年上升趋势, 2017与2018年的不合格率间比较,差异有统计学意义(P<0.05);不合格率由高到低依次为ALT(0.43%)、HBsAg(0.29%) .抗-TP(0.27%)、HIV/抗HIV(0.13%) .抗-HCV0.119%) .异常终止(0.09% )和NAT(0.03%);ALT和异常终止不合格率呈逐年上升趋势,HBsAg和HIV抗HIV不合格率呈逐年下降趋势,梅毒和核酸检测不合格率呈先升后降趋势,抗-HCV不合格率呈先降后升趋势。结论ALT .抗-TP和HBsAg不合格是导致实验室检测不合格的主要原因,采前快检工作有待进一步改进。

Analysis of unqualified blood test in Shandong Blood Center

ObjectiveTo understand the unqualified laboratory test of voluntary blood donors in Shandong Blood Center,and to provide a reference for further improving the utilization rate of voluntary blood donation resources. Methods The data of unqualified blood donors in Shandong Blood Center from January 2016 to December 2018 were retrospectively analyzed. According to different modes, they were divided into rapid detection and laboratory detection, and thedata of unqualified items were analyzed. Results A total of 312 780 people were detected rapidly before blood donation, and the failure rate was 5.67%(17736/312780). The unqualified rate of laboratory test was 1.35% (3942/291799),which showed an increasing trend year by year. There was a significant difference between 2017 and 2018(P<0.05).The unqualified rates from high to low were ALT (0.43%), HBsAg (0.29%), anti-TP (0.27%), HIV/anti-HIV (0.13%),anti-HCV (0.11%), abnormal termination (0.09%) and NAT (0.03%). The unqualified rates of ALT and abnormal termi-nation increased year by year, the unqualified rates of HBsAg and HIV/anti-HIV decreased year by year, the unqualified rates of syphilis and nucleic acid detection increased first and then decreased, and the unqualified rate of anti-HCV decreased first and then increased. Conclusion The unqualified ALT, anti-TP, and HBsAg are the main causes ofunqualified laboratory tests, and the rapid detection before blood collection needs further improvement.