双心治疗和单心治疗慢性心力衰竭患者疗效的比较

目的 比较慢性心力衰竭(CHF)患者给予双心治疗和单心治疗的效果。方法 将住院CHF患者200例随机分组为单心治疗组(100例)和双心（心脏加心理）治疗组(100例)进行对比研究,对双心治疗组进行强化性心理疏导及心力衰竭(HF)常识教育及日常合理生活方式教育3个月,比较两组3个月后心理评估分数的变化。并对两组患者同时随访1年,观察两组患者MACE事件发生率的差异性。结果 CHF患者通过心理疏导及HF教育后,3个月后单心组和双心组患者HAMD评分分别为:(23±6)、(12±4)分,两组评分之间存在明显差异性（P<0.05）;3 个月后单心组HAMA评分 （23±4）分,双心组（12±4）分,与入院时比较前者上升后者显著下降（均P<0.05）,两组组间比较差异有统计学意义（P<0.05）。随访1年,双心治疗组MACE发生率显著低于单心治疗组(P<0.05)。结论 双心治疗CHF患者的疗效优于单心治疗。

Comparison of the efficacy of psycho-cardiology treatment and single cardiology treatment in patients with chronic heart failure

AIM To investigate the relationship between glucose fluctuation and macrovascular complications in type 2 diabetes mellitus (T2DM). METHODS Patients with T2DM were included in the study. The patients were divided into macrovascular complications group (66 cases) and non-macrovascular complications group (76 cases). General clinical data and laboratory indexes of the subjects were recorded. Continue glucose monitoring (CGM) was performed in both groups. RESULTS Age, duration of DM, the percentage of hyperglycemia, the area under curve (AUC) above 11.1 mmol/L, MBG, incidence of hypoglycemia, SDBG, MAGE and LAGE were higher in the macrovascular complications group than in the non-macrovascular complications group (all P<0.05 or P<0.01). There was no significant difference in the ratio of gender, smoker, hypertension, types of antidiabetic drugs, serum lipids, alanine aminotransferase, aspartate aminotransferase, FPG and HbA1c between the two groups. Stepwise logistic regression analyses indicated that macrovascular complications were positively related with age and MAGE independently. Macrovascular complications were positively related with age, duration of DM, percentage of hyperglycemia, area under curve (AUC) above 11.1 mmol/L, incidence of hypoglycemia, MBG, 2hPPG, SDBG, MAGE and LAGE using Spearman’s correlation analysis. CONCLUSION Macrovascular complications were positively related with MAGE in type 2 diabetes mellitus.