| 高效液相色谱法测定连朴饮不同煎液中栀子苷的含量 |
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| 引用本文： | 冯华,聂明华,邹孔强,王祥培,罗秀琼.高效液相色谱法测定连朴饮不同煎液中栀子苷的含量[J].中国医院用药评价与分析,2012(9):809-811. |
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| 作者姓名： | 冯华 聂明华 邹孔强 王祥培 罗秀琼 |
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| 作者单位： | 遵义市食品药品检验所;贵阳中医学院 |
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| 基金项目： | 遵义市中药现代化科技产业研究开发专项项目课题(市科合中药专字[2009]4号) |
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| 摘 要： | 目的:考察用合煎液(传统汤剂)、分煎液(配方颗粒汤剂)方法制备的连朴饮汤剂中栀子苷含量的变化。方法:建立高效液相色谱(HPLC)法,采用Diamonisl C18柱(200 mm×4.6 mm,5μm);流动相为乙睛∶水(20∶80);流速为1 mL·min-1;检测波长为238 nm。结果:连朴饮分煎液中栀子苷平均含量比合煎液中栀子苷平均含量高。结论:与传统汤剂比较,连朴饮配方颗粒汤剂中栀子苷的含量高。
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| 关 键 词： | 连朴饮 栀子苷 合煎 分煎 高效液相色谱法 |
Determination of Geniposide in Mixed vs.Separated Decoctions of Lian Pu Drink by HPLC |
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| FENG Hua,NIE Ming-hua,ZOU Kong-qiang,WANG Xiang-pei,LUO Xiu-qiong.Determination of Geniposide in Mixed vs.Separated Decoctions of Lian Pu Drink by HPLC[J].Evaluation and Analysis of Drug-Use in Hospital of China,2012(9):809-811. |
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| Authors: | FENG Hua NIE Ming-hua ZOU Kong-qiang WANG Xiang-pei LUO Xiu-qiong |
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| Institution: | 1(Zunyi Institute for Food & Drug Control,Guizhou Zunyi 563002,China;2.Guiyang College of Traditional Chinese Medicine,Guiyang 550002,China) |
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| Abstract: | OBJECTIVE: To investigate the content change of geniposide in of Lian Pu Drink prepared by mixed decoction(traditional decoction) method or separated decoction(decoction of dispensing granules) method.METHODS: The content of geniposide was determined by HPLC using Diamonisl C18 column(5 μm,4.6 mm×200 mm) with a mobile phase of CH3CN∶water(20∶80) at a flow rate of 1 mL·min-1 and a detection wavelength of 238 nm.RESULTS: The mean content of geniposide in separated decoction of Lian Pu Drink was higher than in its mixed decoction.CONCLUSION: The content of geniposide in decoction of dispensing granules of Lian Pu Drink was higher than in its traditional decoction. |
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| Keywords: | Lian Pu Drink Geniposide Mixed decoction Separated decoction HPLC |
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