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银杏叶注射液联合奥扎格雷钠治疗急性脑梗死的疗效及对C反应蛋白的影响
引用本文:张义军,王海庚,董继霞. 银杏叶注射液联合奥扎格雷钠治疗急性脑梗死的疗效及对C反应蛋白的影响[J]. 中国医院用药评价与分析, 2012, 0(10): 930-932
作者姓名:张义军  王海庚  董继霞
作者单位:首钢矿山医院神经内科
摘    要:目的:探讨银杏叶注射液联合奥扎格雷钠治疗急性脑梗死的疗效及对C反应蛋白的影响。方法:选取2011年1月—2012年1月收治的急性脑梗死患者共160例,以随机抽样法分为观察组和对照组,其中对照组采用常规治疗及给予奥扎格雷钠治疗,观察组在此基础上加用银杏叶注射液治疗。结果:治疗后观察组的神经功能缺损评分明显低于对照组(P〈0.05);2组总有效率比较,差异具有统计学意义(91.25%vs.75.00%,P〈0.05);治疗后观察组患者C反应蛋白水平明显低于对照组(P〈0.05)。结论:银杏叶注射液联合奥扎格雷钠治疗急性脑梗死,疗效确切,且能够有效地降低C反应蛋白,值得在临床上推广应用。

关 键 词:银杏叶注射液  奥扎格雷钠  急性脑梗死  C反应蛋白

Efficacy of Ginkgo Leaf Plus Sodium Ozagrel for Acute Cerebral Infarction and Its Impact on C Reactive Proteins
ZHANG Yi-jun,WANG Hai-geng,DONG Ji-xia. Efficacy of Ginkgo Leaf Plus Sodium Ozagrel for Acute Cerebral Infarction and Its Impact on C Reactive Proteins[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2012, 0(10): 930-932
Authors:ZHANG Yi-jun  WANG Hai-geng  DONG Ji-xia
Affiliation:(Dept.of Neurology,Shougang Mining Hospital,Hebei Qian’an 064404,China)
Abstract:OBJECTIVE:To evaluate the curative efficacy of Ginkgo leaf plus sodium ozagrel for acute cerebral infarction(ACI) and its impact on C reactive protein(CRP).METHODS: 160 ACI patients treated from Jan.2011 to Jan.2012 in our hospital were randomized to either trial group or control group treated with conventional therapy plus sodium ozagrel,whereas the trial group received add-on Ginkgo leaf injection.RESULTS: The neurologic impairment score in the trial group was significantly lower than in the control group(P<0.05);and there were statistically significant differences between the trial group and the control group in total response rate(91.25% vs.75.00%,P<0.05).The CRP level in the trial group was significantly lower than in the control group(P<0.05).CONCLUSION: Addition of Ginkgo leaf injection to sodium ozagrel in treating ACI resulted in proved efficacy and reduction of CRP level,hence the therapy is worthy of wide clinical use.
Keywords:Ginkgo leaf injection  Sodium ozagrel  Acute cerebral infarction  C reactive protein
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