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123例药品不良反应报告分析
引用本文:李激扬,柏冬红,刘静,张颖,张明文. 123例药品不良反应报告分析[J]. 中国医院用药评价与分析, 2012, 0(2): 158-161
作者姓名:李激扬  柏冬红  刘静  张颖  张明文
作者单位:中国中医科学院西苑医院药剂科
摘    要:目的:分析我院药品不良反应(ADR)发生的规律和特点,促进临床合理用药。方法:采用回顾性分析方法,对我院2010年1—12月收集的123例ADR报告进行统计分析。结果:123例(144例次)ADR报告中,中(成)药引起的ADR居首位(72例次,占50.00%),其次为抗感染药(35例次,占24.31%);抗感染药中氟喹诺酮类ADR发生率最高,为48.57%(17例次);在123例ADR报告中,新的ADR为44例,其中中(成)药相关的新的ADR最多(37例)。结论:在今后的ADR监测中应加强对中(成)药及抗感染药的监测,并有针对性地实施ADR防治措施,降低用药风险。

关 键 词:药品不良反应  中(成)药  氟喹诺酮类  新的ADR

Adverse Drug Reactions:Analysis of 123 Cases
LI Ji-yang,BAI Dong-hong,LIU Jing,ZHANG Ying,ZHANG Ming-wen. Adverse Drug Reactions:Analysis of 123 Cases[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2012, 0(2): 158-161
Authors:LI Ji-yang  BAI Dong-hong  LIU Jing  ZHANG Ying  ZHANG Ming-wen
Affiliation:(Dept.of Pharmacy,Xiyuan Hospital of China Science Academy of Traditional Chinese Medicine,Beijing 100091,China)
Abstract:OBJECTIVE:To analyze the regularity and characteristics of adverse drug reactions(ADRs) in our hospital so as to promote clinical rational drug use.METHODS: A total of 123 ADR cases(totaled 144 cases/times) collected in our hospital during the Jan.-Dec.period of 2010 were analyzed retrospectively.RESULTS: Of the total 144 cases/times,72 cases/times(50.00%) were induced by Chinese patent medicine and 35 by anti-Infective drugs.Of all the anti-infective drugs,fluoroquinolone took the lead in ADR incidence with 17 cases/times(48.57%).Of the total 123 ADR cases,44 were new ADR cases in which 37 cases were induced by Chinese patent medicine.CONCLUSION: Great importance should be attached to Chinese patent medicine and anti-infective drugs in ADR monitoring and measures should be taken aimed at ADR prevention and cure to reduce the risks of drug use.
Keywords:Adverse drug reaction  Chinese patent medicine  Fluoroquinolones  New ADR
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