2009—2011年北京大学深圳医院病区口服质子泵抑制剂应用分析

目的:了解我院病区口服质子泵抑制剂(PPI)的使用情况,为临床安全、经济、高效用药提供参考。方法:对2009—2011年我院病区口服PPI的品种、销售金额、用药频度(DDDs)、限定日费用(DDC)进行统计分析。结果:2009—2011年我院病区口服PPI的用药量呈先升后降趋势。销售金额和DDDs排序埃索美拉唑镁肠溶片均居首位,奥美拉唑镁肠溶片(洛赛克MUPS,20 mg)排序居第2位;奥美拉唑肠溶片(10 mg)的DDDs呈稳步增长趋势,金额序号/DDDs序号为1.67,序号比最大,表明该药的使用频度较高,但其DDC却相对较低;兰索拉唑肠溶片从2010到2011年呈快速增长趋势(137%)。结论:我院病区口服PPI应用基本合理。

Analysis on The Use of Oral Proton Pump Inhibitors in The Inpatients of Peking University Shenzhen Hospital During 2009-2011

OBJECTIVE: To investigate the use of oral proton pump inhibitors(PPI) in the inpatients of Peking University Shenzhen Hospital so as to provide reference for clinical safe,economical and effective use of PPI.METHODS: The total consumption sum,the DDDs and the defined daily cost(DDC) of oral PPI in the inpatients of our hospital from 2009 to 2011 were given a statistical analysis.RESULTS: The total consumption amount of oral PPI in the inpatients of our hospital from 2009 to 2011 showed an increase followed by a decrease.Esomeprazole magnesium enteric-coated tablets topped the list in terms of both consumption sum and DDDs,followed by omeprazole magnesium enteric-coated tablets(losec mups,20 mg).The DDDs of omeprazole(10 mg) showed a steady growth trend.The ratio of the consumption sum serial number to the DDDs serial number of enteric-coated tablets was the maximum at 1.67,indicating the highly frequent use of this drug;however,which had low DDC.The DDDs of lansoprazole increased rapidly by 137% in 2011 over the previous year.CONCLUSION: The use of oral PPI in the inpatients of our hospital was reasonable on the whole.