重症监护病房患者应用哌拉西林/舒巴坦的合理性分析

目的:评价遂宁市中心医院重症患者哌拉西林/舒巴坦的应用情况,为合理用药提供依据。方法:采用回顾性分析方法,调查我院重症监护病房2010年1月—2011年3月使用哌拉西林/舒巴坦150例,统计、分析基础疾病、细菌学培养及药敏试验结果,评价用药合理性。结果:在150例患者中,治疗用药112例,有效97例,无效7例,死亡8例,总有效率为86.6%;预防用药38例,有效35例,无效3例,总有效率为92.1%。结论:哌拉西林/舒巴坦对重症患者治疗有效,为保持有效性应促进其合理应用。

Rationality in the Utilization of Piperacillin/Sulbactam for ICU Patients

OBJECTIVE: To evaluate the utilization of piperacillin/sulbactam in Sichuan Suining Municipal Central Hospital in ICU patients so as to provide references for clinical rational use of piperacillin/sulbactam.METHODS: A retrospective study was performed in 150 ICU patients treated with piperacillin/sulbactam from Jan.2010 to Mar.2011.The data regarding the patients’ basic diseases,bacterial culture and drug sensitivity test were analyzed statistically and the rationality of drug use was evaluated.RESULTS: Of the 150 patients,112 received piperacillin/sulbactam for treatment purpose,of whom,97 had response,7 did not have a response,and 8 died,with a total effective rate of 86.6%;38 received drugs for prophylactic purpose,of whom,35 had response and 3 did not have response to treatment,with total effective rate of 92.1%.CONCLUSION: Piperacillin/sulbactam therapy is effective for ICU patients,however,the efficacy of which is dependent on its rational use.