sST2替代NT-proBNP评价心脏术后肾功能不全患者心功能的临床价值

目的 探讨心力衰竭标志物可溶性生长刺激表达因子2(sST2)替代N末端B型脑钠肽前体(NT-proBNP)评价心脏术后肾功能不全患者心功能变化的临床价值.方法 选择2019年1～6月我科心脏外科手术后肾功能不全患者60例作为试验组,其中男34例、女26例,平均年龄49～78(63.3±4.5)岁;另选取心脏术后肾功能正...

Clinical value of sST2 in replacement of NT-proBNP in cardiac function evaluation in renal failure patients after cardiac surgery

Objective To explore the clinical value of soluble suppression of tumorigenesis-2(sST2)in replacement of N-terminal fragment of the brain natriuretic peptide precursor(NT-proBNP)in cardiac function evaluation in renal failure patients after cardiac surgery.Methods Sixty patients with renal insufficiency after cardiac surgery from January 2019 to June 2019 were divided into a test group,including 34 males and 26 females,with an average age of 49-78(63.3±4.5)years.Another 60 patients with normal renal function were divided into a control group,including37 males and 23 females,with an average age of 53-77(61.7±3.8)years.The perioperative left ventricular ejection fraction,cardiac troponin T,creatine kinase-MB,sST2 and NT-proBNP were compared.Results In patients of the test group,the NT-proBNP level increased significantly during perioperative period,and the change range was different from other cardiac function indexes.The change of sST2 in perioperative period was similar to other cardiac function indexes,which could reflect the change degree of cardiac function after operation.Conclusion sST2 is more important to reflect the change degree of cardiac function in patients with renal dysfunction after cardiac surgery than NT-proBNP.