Assessing new strategies for TB diagnosis in low- and middle-income countries |
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| Authors: | Afrânio Kritski Paula I. Fujiwara Maria Armanda Vieira Antonio Ruffino Netto Martha Maria Oliveira Gisele Huf S. Bertel Squire |
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| Affiliation: | 1. Rede TB, Rio de Janeiro, RJ, Brazil;2. Academic Tuberculosis Program, Medical School, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil;3. International Union Against Tuberculosis and Lung Disease, Paris, France;4. Medical School, Universidade de São Paulo, Ribeirão Preto, SP, Brazil;5. Liverpool School of Tropical Medicine, Liverpool, United Kingdom;6. National Institute for Quality Control, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil |
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| Abstract: | In this manuscript, we report the current situation of tuberculosis globally and in Brazil, the need for new strategies toward tuberculosis control, focusing on new diagnostic technologies. Critical comments are given on the state of the art regarding the evaluation of new health technologies, degree of scientific evidence needed, evaluation of clinical impact, cost-effectiveness of incorporation into the health system and the social impact. |
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