原发性甲状旁腺功能亢进症的诊断和治疗进展

原发性甲状旁腺功能亢进症(PHPT)是一种钙代谢紊乱疾病,其典型特征是血钙、PTH、尿钙升高,容易累及机体多个系统。该病主要是由于甲状旁腺组织的良性腺瘤导致,少部分为甲状旁腺增生或甲状旁腺癌。随着体检意识的增强,无症状型PHPT患者所占比例逐渐增加。该病可通过手术切除病变的甲状旁腺而治愈,大多预后良好,但少部分情况复杂,诊治较为困难。目前对该病的诊疗方面尚存许多争议,本文就PHPT诊治过程中的相关进展进行综述。

Progress in diagnosis and treatment of primary hyperparathyroidism

Primary hyperparathyroidism(PHPT)is a disorder of calcium metabolism,which is characterized by elevated blood calcium and PTH urine calcium,which is easy to involve multiple systems.The disease is mainly caused by a benign adenoma of parathyroid tissue,a few of which are parathyroid hyperplasia or parathyroid adenocarcinoma.As awareness of physical examination increased,the proportion of asymptomatic PHPT patients gradually increased.The disease can be cured by surgical resection of the parathyroid gland,most of which is a real good prognosis,but a few of them are complex and difficult to diagnose and treat.At present,there continue to be many controversies about the diagnosis and treatment of PHPT.This article is a review of the progress in the diagnosis and treatment of PHPT.