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Acute pancreatitis caused by bortezomib
Authors:Tevfik Solakoglu  Pinar Akyol  Tekin Guney  Imdat Dilek  Roni Atalay  Huseyin Koseoglu  Ebru Akin  Aylin Demirezer Bolat  Naciye Semnur Buyukasik  Osman Ersoy
Affiliation:1. Department of Gastroenterology, Ankara Ataturk Research and Education Hospital, Bilkent Street, 06800 Ankara, Turkey;2. Department of Internal Medicine, Ankara Ataturk Research and Education Hospital, Turkey;3. Department of Haematology, Ankara Ataturk Research and Education Hospital, Turkey;4. Faculty of Medicine, Department of Gastroenterology, Yildirim Beyazit University, Turkey
Abstract:Drug-induced pancreatitis has been reported rarely. Bortezomib is a selective and reversible proteasome inhibitor used for the treatment of patients with multiple myeloma (MM). Recently, one case report about acute pancreatitis (AP) caused by bortezomib was published in the international literature. Herein we report a case of AP in a 67-year-old male on bortezomib therapy. On the fourth day after the first administration of bortezomib, the patient admitted to the hospital with symptoms of AP. The common etiological factors for AP were all excluded. Than the patient was diagnosed as bortezomib-induced pancreatitis.
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