| HPLC法测定消石利胆胶囊中黄芩苷的含量 |
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| 引用本文： | 陈喜生,胡滨湘.HPLC法测定消石利胆胶囊中黄芩苷的含量[J].中国现代药物应用,2009,3(15):19-20. |
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| 作者姓名： | 陈喜生 胡滨湘 |
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| 作者单位： | 1. 湖南娄底市药品检验所,417000
2. 娄底市中心医院 |
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| 摘 要： | 目的建立测定消石利胆胶囊中黄芩苷含量的HPLC测定方法。方法采用Shim—pack VP—ODS C18柱，乙腈-0.2％磷酸（27：73）为流动相，检测波长为280nm，流速1．0ml·min-1。结果黄芩苷在0．651μg-1．954μg范围内与峰面积呈良好线性关系，r=-0．9999，平均加样回收率为99．59％，RSD为1．1％（n=6）。结论该方法简便、准确，专属性强，重现性好，可用于消石利胆胶囊的质量控制。
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| 关 键 词： | 消石利胆胶囊 黄芩苷 HPLC |
Determination of Baicalin in Xiaoshilidan Capsules by HPLC |
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| Chen Xishen,Hu Binxiang.Determination of Baicalin in Xiaoshilidan Capsules by HPLC[J].Chinese Journal of Modern Drug Application,2009,3(15):19-20. |
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| Authors: | Chen Xishen Hu Binxiang |
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| Institution: | Chen Xishen, Hubinxian(1 The Institute for Drug Control of Loudi, Hunan Loudi 417000, Chino,. 2 The Central Hospital of Loudi) |
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| Abstract: | Objective To establish a method for determination of Baicalin in Xiaoshilidan Capsules by HPLC. Methods A Shim-pack VP-ODS C18 Colunm was used. The mobile phase was Acetonitrile-0.2% Phosphoric acid （27：73）, the detecting wavelength was at 280nm, the flow rate was 1.0ml·min-1. Results The linear range of Baicalin was within 0.651？g-1.954？g. r=0.9999,tbe average sample recovery was 99.59% with RSD of 1.1%（n=6）. Conclusion This method has good repeatability,flexibility and high sensitivity. It can be used for quality control of Xiaoshilidan Capsules. |
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| Keywords: | HPLC |
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