| 干细胞在视神经损伤修复中的应用 |
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| 引用本文： | 张敬学,王宁利,马建民. 干细胞在视神经损伤修复中的应用[J]. 眼科研究, 2009, 27(11): 1044-1047 |
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| 作者姓名： | 张敬学 王宁利 马建民 |
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| 作者单位： | 首都医科大学附属北京同仁医院眼科中心,北京,100730 |
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| 摘 要： | 许多致盲性眼病是由视网膜神经节细胞（RGCs）损伤造成的,目前临床上缺乏有效的治疗方法。最近的研究显示干细胞可以替代或再生RGCs,从而有望修复受损的视功能。这些结果提供了新颖的视神经再生模式,但具体到临床应用,仍存在一系列问题需要解决。就应用干细胞再生视神经的研究进展进行综述。
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| 关 键 词： | 视网膜神经节细胞 干细胞 视神经再生 移植 |
Research advance in application of stem cells in optic nerve regeneration |
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| Zhang Jingxue,Wang Ningli,Ma Jianmin. Research advance in application of stem cells in optic nerve regeneration[J]. Chinese Ophthalmic Research, 2009, 27(11): 1044-1047 |
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| Authors: | Zhang Jingxue Wang Ningli Ma Jianmin |
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| Affiliation: | Zhang Jingxue, Wang Ningli, Ma Jianmin( Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China) |
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| Abstract: | Lots of blinding diseases are caused by retinal ganglion cells apoptosis, but there is no the effective and ideal therapy in clinic currently. Recent study showed that stem cells can be an alternative renewable source of retinal ganglion cells, and they may be potential to repair the visual function. These results provide a new model of optic nerve regeneration for the treatment of these blinding diseases. But, some problems in clinical applications are waiting for further solving. Applications of stem cells in optic nerve regeneration is reviewed in this paper. |
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| Keywords: | retinal ganglion cell stem cell optic nerve regeneration transplantation |
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