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Risk of medically attended local reactions following diphtheria toxoid containing vaccines in adolescents and young adults: A Vaccine Safety Datalink study |
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| Authors: | Lisa A. Jackson Onchee Yu Jennifer Nelson Edward A. Belongia Simon J. Hambidge Roger Baxter Allison Naleway James Nordin James Baggs John Iskander |
| Affiliation: | 1. Group Health Center for Health Studies, 1730 Minor Ave, Ste 1600, Seattle, WA 98101, United States;2. Epidemiology Research Center, Marshfield Clinic Research Foundation, Marshfield, WI, United States;3. Kaiser Permanente Institute for Health Research, Denver, CO, United States;4. Denver Health Community Health Services, Denver, CO, United States;5. Department of Biostatistics, University of Washington, Seattle, WA, United States;6. Kaiser Permanente Vaccine Study Center, Oakland, CA, United States;g Kaiser Permanente Northwest, Portland, OR, United States;h HealthPartners, Minneapolis, MN, United States;i Centers for Disease Control and Prevention, Atlanta, GA, United States |
| Abstract: | Three vaccines currently recommended for adolescents (Tdap, Td, and MCV4 meningococcal conjugate vaccine) contain diphtheria toxoid. While the safety of individual diphtheria toxoid containing vaccines has been evaluated, less is known regarding the safety of administration of two or more of these vaccines, either concomitantly or sequentially. This study evaluated the risk of medically attended local reactions in adolescents and young adults with varying patterns of receipt of diphtheria toxoid containing vaccines. In general the risk of medically attended local reactions was low and did not differ with concomitant or sequential administration of diphtheria toxoid containing vaccines. |
| Keywords: | Vaccine safety Tetanus vaccine Pertussis vaccine |
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