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Reduction in hepatitis B virus seroprevalence among U.S.-born children of foreign-born Asian parents—Benefit of universal infant hepatitis B vaccination
Authors:Carrie M Shuler  Anthony E Fiore  Ruth Neeman  Beth P Bell  Wendi Kuhnert  Sandra Watkins  Kimberly Kilgour  Kathryn E Arnold
Institution:1. Notifiable Diseases Epidemiology Section, Georgia Department of Human Resources, Division of Public Health, Atlanta, GA, United States;2. Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, United States;3. Division of Viral Hepatitis, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States;4. Hepatitis Laboratory, Division of Viral Hepatitis, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, United States;5. Georgia Public Health Laboratory, Georgia Department of Human Resources, Division of Public Health, Atlanta, GA, United States
Abstract:We demonstrate that after implementation of recommendations for universal infant hepatitis B vaccination, HBV infection prevalence among children of foreign-born Asian parents in Georgia declined dramatically; horizontal transmission of infection within households has occurred infrequently; and the vast majority of infants and children have received the recommended hepatitis B vaccinations. These results provide evidence of the success of the hepatitis B infant vaccination program and highlight its potential impact on reducing chronic HBV infection morbidity and mortality among U.S. populations at high risk.
Keywords:Hepatitis B immunizations  Pediatrics
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