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Significance of serum neuron-specific enolase in patients with acute traumatic brain iniurv
引用本文:官卫,杨伊林,夏为民,李璐,龚德生. Significance of serum neuron-specific enolase in patients with acute traumatic brain iniurv[J]. 中华创伤杂志(英文版), 2003, 0(4)
作者姓名:官卫  杨伊林  夏为民  李璐  龚德生
作者单位:Department of Neurosurgery,Third Hospital Affiliated to Suzhou University,Changzhou,213003,China,Department of Neurosurgery,Third Hospital Affiliated to Suzhou University,Changzhou,213003,China,Department of Neurosurgery,Third Hospital Affiliated to Suzhou University,Changzhou,213003,China,Department of Neurosurgery,Third Hospital Affiliated to Suzhou University,Changzhou,213003,China,Department of Neurosurgery,Third Hospital Affiliated to Suzhou University,Changzhou,213003,China
摘    要:Objective: To study the association between serum neuron-specific enolase ( NSE) and the extent of brain damage and the outcome after acute traumatic brain injury (TBI).Methods: The release patterns of serum NSE in 78 patients after acute TBI were analyzed by using the enzyme linked immunosobent assay. The levels of NSE were compared with Glasgow coma scale, the category of brain injury and the outcome after 6 months of injury.Results: There were different NSE values in patients with minor ( 12.96 μg/L ±2.39 μg/L ), moderate ( 23.44 μg/L ±5.33 μg/L ) and severe brain injury ( 42.68 μg/L ±4.57 μg/L ). After severe TBI, the concentration of NSE in patients with epidural hematomas was 13.38 μg/L±4.01 μg/L, 24.03 μg/L±2.85 μg/L in brain contusion without surgical intervention group, 55.20 μg/L ±6.35 μg/L in brain contusion with surgical intervention group, and 83.85 μg/L ± 15.82 μg/L in diffuse brain swelling group. There were close correlations between NSE values and Glasgow coma scale


Significance of serum neuron-specific enolase in patients with acute traumatic brain iniurv
GUAN Wei,YANG Yi-lin,XIA Wei-min,LI Lu and GONG De-sheng. Significance of serum neuron-specific enolase in patients with acute traumatic brain iniurv[J]. Chinese journal of traumatology, 2003, 0(4)
Authors:GUAN Wei  YANG Yi-lin  XIA Wei-min  LI Lu  GONG De-sheng
Affiliation:GUAN Wei,YANG Yi-lin,XIA Wei-min,LI Lu and GONG De-sheng Department of Neurosurgery,Third Hospital Affiliated to Suzhou University,Changzhou,213003,China
Abstract:
Keywords:Brain injuries  Glasgow coma scale  Neuron specific enolase
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