肢体爆炸伤海水浸泡后皮肤软组织的病理改变

目的探讨肢体爆炸伤海水浸泡后皮肤软组织的病理变化特点，为海战伤中采用组织移植等修复方法处理伤口提供理论依据。方法选用纸壳爆破雷管炸伤家兔后肢，将致伤家兔分别置于海水中浸泡30min和1h，并分别在浸泡后2、6、12h取材，肉眼、光镜观察组织形态变化，并与单纯爆炸伤和淡水浸泡组进行比较。结果肢体爆炸伤海水浸泡后皮肤损伤程度、范围以及炎症反应明显重于单纯火器伤组；浸泡时间越长，组织损伤越重；海水浸泡后嗜酸性粒细胞明显增多，与单纯火器伤组和淡水浸泡组有明显区别。结论爆炸伤后海水浸泡不但加重了皮肤组织的继发损伤，而且伤口全部基染，并司见大量嗜酸性粒细胞。本研究结果对海战中研究伤口修复的方法有一定的指导意义。

Soft-tissue pathology changes in explosive injuries after seawater immersion

Objective To explore soft-tissue pathological changes of explosive injuries after seawater immersion, and to provide theoretical support for wound treatment in naval battles. Methods Rabbit rear limbs were wounded by paper-shell detonator, and subsequently immersed in seawater for 30 rain and for lh respectively. Morphological changes of the injuries were observed with bare eyes and optical microscope 2h, 6h, and 12h after seawater immersion, and were compared with the firearm wounded group and freshwater immersion group. Results Compared with the firearm wounded group, the seawater immersion group were more serious in terms of damnification extent, area and inflammation reaction. The tissue injuries got worse with the increase of immersion time and there was an obvious increase in the number of eosinophilic granulocyte after seawater immersion, which was significantly different from the firearm wounded group and freshwater immersion group. Conclusions Seawater immersion of explosive injuries could make skin tissue subsequent injuries worse, wound contracted, and eosinophilic granulocyte increase, which might be instructive for wound treatment in naval battles.