Clonality of Streptococcus pneumoniae serotype 1 isolates from pediatric patients in the United States |
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| Authors: | Gonzalez Blanca E,Hulten Kristina G,Kaplan Sheldon L,Mason Edward O US Pediatric Multicenter Pneumococcal Surveillance Study Group |
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| Affiliation: | Division of Infectious Diseases, Baylor College of Medicine, Texas Children's Hospital, Mail Code 3-2371, 6621 Fannin St., Houston, TX 77030, USA. |
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| Abstract: | We compared Streptococcus pneumoniae serotype 1 isolates causing disease among children in six geographic regions of the United States to determine genetic relatedness. Genomic fingerprints were determined by repetitive element polymorphism PCR (Rep-PCR). Multilocus sequence type characterization was performed on selected isolates. Four different genomic banding patterns were identified by Rep-PCR. One profile (clone 1) was predominant and matched sequence type 227. |
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