认知康复训练治疗脑损伤后认知功能障碍的Meta分析

目的:系统评价认知康复训练治疗脑损伤后认知障碍的疗效。方法:计算机检索CNKI、VIP、CBM、万方及PubMed数据库,查找关于认知康复训练治疗脑损伤后认知障碍的临床随机对照试验。对纳入的研究逐个进行质量评价,并进一步对治疗后认知训练组和对照组的有效率、简易智力状况检查法(MMSE)、日常生活活动能力(ADL)、洛文斯顿认知功能评定测验(LOTCA)评分进行Meta分析。结果:16个研究共1281例患者符合纳入标准。结果显示,认知训练组的总有效率、MMSE、ADL及LOTCA评分均明显优于对照组(P0.05,0.01)。结论:认知康复训练治疗脑损伤后认知障碍患者可一定程度上减轻认知障碍的程度,提高患者的自我生活能力。

Meta-analysis on treatment of cognitive impairment after brain injury by cognitive rehabilitation training

Objective: To systematically assess the efficacy of cognitive rehabilitation training in treating cognitive impairment after brain injury. Methods: A computer searched CNKI, CBM, VIP, WanFang Data and Pubmed for randomized controlled trials (RCT) of a cognitive rehabilitation training for the treatment of cognitive impairment after brain injury. The quality of the included studies was evaluated one by one, and the effective rate, MMSE, ADL and LOTCA scores of the cognitive training group and the control group were further analyzed by Meta. Results: Sixteen trials with a total of 1281 subjects were finally enrolled. The results of Meta analysis showed that the effective rate, and scores of MMSE, ADL and LOTCA were significantly higher in the cognitive rehabilitation training group than in the control group. Conclusion: Cognitive rehabilitation training in treating cognitive impairment after brain injury could reduce the degree of cognitive impairment, and improve the patients'' self-care ability.