| 东北红豆杉原料中紫杉醇的提取及测定 |
| |
| 引用本文： | 阎家麒 刘虹. 东北红豆杉原料中紫杉醇的提取及测定[J]. 中国医药工业杂志, 1994, 25(10): 433-436 |
| |
| 作者姓名： | 阎家麒 刘虹 |
| |
| 作者单位： | 郑州牧业工程高等专科学校，河南省科学院应用物理研究所，河南省分析测试中心，新乡市高科生物化学工程有限公司 |
| |
| 摘 要： | 将磨碎的红豆杉树皮和针叶采用二氯甲烷－甲醇抽提、二氯甲烷－水两相萃取，经间歇过滤、硅藻土涂渍后上硅胶柱色谱分离，再在含水甲醇中结晶，得含量＞９０％的紫杉醇。总产率为干叶重的０．００６％，干树皮重的０．００４％。
|
| 关 键 词： | 紫杉醇，天然产物，提取，测定 |
PREPARATION OF TAXOL |
| |
| YAN Jia-Qi,LIU Hong,WANG Jiu-Yi,ZHAO Min. PREPARATION OF TAXOL[J]. , 1994, 25(10): 433-436 |
| |
| Authors: | YAN Jia-Qi LIU Hong WANG Jiu-Yi ZHAO Min |
| |
| Abstract: | Ground barks and ground needles of Taxus cuspidata were extracted with CH2Cl2-MeOH to yield native extract.This extract was partitioned between CH2Cl2 and H2O to give a CH2Cl2 extract,which was treated by batch filtration.This fraction was coated onto Celite-545 and loaded onto Sigel column,followed by crystallization from aqueous MeOH to afford gave taxol(content>90%).The overall yield of taxol was 0.006% and 0.004% of dry needles and barks respectively. |
| |
| Keywords: | taxol natural products extraction determination |
| 本文献已被 CNKI 维普 等数据库收录！ |
