| 脂质体透皮给药研究进展 |
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| 引用本文： | 黄寿吾,王大林.脂质体透皮给药研究进展[J].中国医药工业杂志,1994,25(11):522-525. |
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| 作者姓名： | 黄寿吾 王大林 |
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| 作者单位： | 洛阳医学高等专科学校附属医院，上海医药工业研究院 |
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| 摘 要： | 对脂质体与表皮角质层的作用作了综述。脂质体能增加角质层的含水量及水合作用，并与角质细胞间的脂质结合，可以削弱表皮角质层的屏障功能，促进透皮吸收。
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| 关 键 词： | 脂质体，透皮给药系统，透皮吸收 |
ADVANCES OF RESEARCH OF LIPOSOME AS TRANSDFRMAL DRUG DELIVERY SYSTEM |
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| Authors: | HUANG Shou-Wu WANG Da-Lin FU Chao-Hong |
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| Abstract: | The interaction between liposome and horny layer and update results obtained both in vitro and in clinical studies are reviewed. Liposome may increase humidity and hydration in horny layer as well as integration into the intercellular lipid of corny layer so as to decrease the barrier function of horny layer of epidermis,and promote transdermal absorption of drugs. |
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| Keywords: | liposome transdermal drug delivery system percutaneous absorption |
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