表观弥散系数值的离散系数在胰腺癌及肿块型胰腺炎鉴别诊断中的应用

目的：探讨表观弥散系数（ADC）值的离散系数对于胰腺癌及肿块型胰腺炎鉴别诊断的应用价值.方法：收集胰腺癌患者28例,肿块型胰腺炎患者7例,行磁共振弥散加权成像（DWI）检查,分别测量每一病灶ADC值的均值（x）及标准差（s）,并计算每一个病灶ADC值的离散系数（CV,CV=s/x）.采用Student＇st检验对两组患者病灶ADC值均值及CV进行比较.结果：胰腺癌组ADC值均值为1.46±0.29,肿块型胰腺炎组ADC值均值为1.58±0.28,经Student＇s t检验显示两组间无显著差异（t=1.02,P=0.32）;胰腺癌组ADC值CV为0.16±0.06,肿块型胰腺炎组CV为0.10 ±0.04,两组CV之间具有显著差异（t=2.44,P=0.02）.结论：胰腺DWI检查中,ADC值CV较ADC值均值对于胰腺癌与肿块型胰腺炎的鉴别诊断具有更高价值.

Application of coefficient variance of apparent diffusion coefficient value in differentiating pancreatic carcinoma from focal pancreatitis

Objective：To evaluate the usefulness of coefficient variance（CV） of apparent diffusion coefficient（ADC） value in differentiating pancreatic carcinoma from focal pancreatitis.Methods：Diffusion weighted MR data were obtained from 28 patients of pancreatic carcinoma and 7 patients of focal pancreatitis.The mean value（x） and standard deviation（s） of ADC value in every lesion were measured.The CV of the lesion was defined as CV=s/x.The x values and CVs were compared between groups using Student＇s t test.Result：The mean value of pancreatic carcinoma was 1.46±0.29,and the mean value of focal pancreatitis was 1.58±0.28.There were no obvious differences between the mean value of pancreatic carcinoma and focal pancreatitis （t=1.02,P=0.32）.CV of pancreatic carcinoma was 0.16±0.06,and CV of focal pancreatitis was 0.10±0.04.CV of pancreatic carcinoma was significantly higher than that of focal pancreatitis（t=2.44,P=0.02）.Conclusion：The CVs of ADC values in lesions were more useful than that of mean value to distinguish pancreatic carcinoma and focal pancreatitis.