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| 实时细胞电子分析技术的应用研究进展简 | |
| 引用本文： | 严国俊,裴燕芳,朱贞宏,,吴洁颖,潘金火. 实时细胞电子分析技术的应用研究进展简[J]. 中国药学杂志, 2014, 49(3): 169-173. DOI: 10.11669/cpj.2014.03.001 |
| 作者姓名： | 严国俊 裴燕芳 朱贞宏 吴洁颖 潘金火 |
| 作者单位： | 1.南京中医药大学药学院, 南京 210023; 2. 艾森生物科学公司, 圣地亚哥CA92121; 3.艾森生物(杭州有限公司, 杭州高通量新药筛选中心, 杭州 310030 |
| 基金项目： | 国家自然科学基金资助项目(81202922);江苏高校优势学科建设工程资助项目(2011ZYX3-004) |
| 摘 要： | 目的 综述实时细胞电子分析技术的研究进展, 为中药研究提供参考。 方法 根据近年来国内外相关文献, 对实时细胞电子分析技术的原理、特点及其应用进行归纳总结。 结果与结论 实时细胞电子分析技术是一种无标记、无侵害的实时细胞电子分析方法。综述了实时细胞电子分析技术的应用研究进展, 为其在药学领域进一步应用发展提供参考, 并对其在中药及复方领域的应用前景进行了展望。 |
| 关 键 词： | 实时细胞电子分析技术 应用进展 中药 药学 |
| 收稿时间： | 2014-03-03; |
Research Progress in Application of Real-Time Cell-based Assay (RTCA) |
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| YAN Guo-jun,PEI Yan-fang,ZHU Zhen-hong,,WU Jie-ying,PAN Jin-huo. Research Progress in Application of Real-Time Cell-based Assay (RTCA)[J]. Chinese Pharmaceutical Journal, 2014, 49(3): 169-173. DOI: 10.11669/cpj.2014.03.001 | |
| Authors: | YAN Guo-jun PEI Yan-fang ZHU Zhen-hong WU Jie-ying PAN Jin-huo |
| Affiliation: | 1.National First-Class Key Discipline for Traditional Chinese Medicine of Nanjing University of Chinese Medicine, Nanjing 210023, China;2.ACEA Biosciences, Inc., San Diego CA92121, USA;3.ACEA BIO (Hangzhou) Co., LTD., Hangzhou High Throughput Drug Screening Center, Hangzhou 310030, China |
| Abstract: | OBJECTIVE To provide reference for further application of RTCA in the field of TCM(traditional Chinese medicine) development, and summarize the RTCA technology application progress in recent years. METHODS The RTCA technology principles, characteristics and applications are summarized based on referring to the related literature in recent years. RESULTS AND CONCLUSION RTCA is a kind of unmarked, non-invasive real-time cell electronic analysis method. It is recently used in drug screening, toxicology evaluation, cell growth, division and death mechanism research. The dynamic real-time analysis of cell is more and more concerned. The RTCA technology application prospects in the field of traditional Chinese medicine and compound are demonstrated. It is hoped to provide reference for further application of RTCA in the field of pharmaceutical development. |
| Keywords: | RTCA application progress traditional Chinese medicine pharmacy |
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