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聚酰胺亲和膜包对透析液中内毒素去除的研究
引用本文:王洪刚,马丽红,汤新强,潘明臣. 聚酰胺亲和膜包对透析液中内毒素去除的研究[J]. 大连医科大学学报, 2008, 30(1): 25-28
作者姓名:王洪刚  马丽红  汤新强  潘明臣
作者单位:大连医科大学,第一临床学院,临床药学教研室,辽宁,大连,116011;中国人民解放军210医院,临床药学教研室,辽宁,大连,116011
摘    要:[目的]研究聚酰胺亲和膜包对透析液中内毒素的去除。[方法]用鲎试剂法测定透析液中内毒素。[结果]①随着流速的增加,内毒素去除率有所下降。②温度对水溶液中内毒素的去除影响不明显。③含白蛋白透析液中内毒素的去除率较低。[结论]聚酰胺亲和膜包可有效去除透析液中内毒素,且可较高的保留各种物质的有效成分。

关 键 词:聚酰胺亲和膜包  透析液  内毒素
文章编号:1671-7295(2008)01-0025-04
收稿时间:2007-11-06
修稿时间:2007-11-21

Study of endotoxin removal in kidney dialysis solution by amide membrane package
WANG Hong-gang,MA Li-hong,TANG Xing-qiang and PAN Ming-chen. Study of endotoxin removal in kidney dialysis solution by amide membrane package[J]. Journal of Dalian Medical University, 2008, 30(1): 25-28
Authors:WANG Hong-gang  MA Li-hong  TANG Xing-qiang  PAN Ming-chen
Affiliation:1 Department of Clinical Pharmacy;the First Affiliated Hospital of Dalian Medical University;Dalian 116011;China;2 Department of Clinical Pharmacy;the 210 Hospital of the PMA;China
Abstract:[ Objective] To study the endotoxin removal in dialysis solution by amide membrane package. [ Methods] Determination TAL (Tachypleus Amebocyte Lysate) endotoxin in dialysis solution. [ Results] (1)With the increase of velocity, endotoxin removal rate has declined. (2)Temperature on endotoxin in aqueous solution is not obvious impact of the removal. (3)In albumin dialysis solution containing endotoxin removal rate is lower. [ Conclusion ] The amide membrane package may effectively remove the endotoxin of dialysis fluid, also may the higher retention each kind of matter effective component.
Keywords:amide membrane package    kidney dialysis solution    endotoxin
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