老年哮喘患者气道反应性测定的应用

目的　主要探讨老年哮喘气道反应性及治疗特点。　方法　老年哮喘50例(激素治疗组28例及非激素治疗组22例)、慢性阻塞性肺疾病(COPD)48例、健康老年人30例。观察肺活量(VC)、一秒率(FEV

Characterization of airway reactiv ity and response to treatment in the eld erly asthma

Objective To explore the characteristics of airway reactivity and effects of steroid treatment on the elderly asthma. Methods We had observed VC,FEV 1,FEV 1/FVC%,MMEF and variability of FEV 1 after bronchial dilator inhalation in 50 asthmatic patients in the elderly(including 28 cases of steroid treatment and 22 cases of non steroid treatment),48 patients with chronic obstructive pulmonary disease(COPD) and 30 healthy elderly subjects.Results The VC,FEV 1,FEV 1/FVC% and MMEF in the elderly asthma were not signifficantly different from COPD( P >0.05),but lower than the healthy elderly subjects( P <0 05).After inhalation of salbutamol,the variability of FEV 1 in the elderly asthma group statistically higher than COPD( P <0 01)and the healthy elderly subjects( P <0 01).The variability of FEV 1 in the elderly asthma group with steroid treatment presented more significant improvement than those of patients without steroid treatment( P <0 05).Conclusions The test of bronchial dilation is a very useful method for diagnosis of the elderly asthma.Glucocorticoid can improve the reactivity of airway and relieve the symptoms.