A Randomized Controlled Trial of OPT-302, a VEGF-C/D Inhibitor for Neovascular Age-Related Macular Degeneration |
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| Affiliation: | 1. Faculty of Life Sciences and Medicine, King’s College London, London, United Kingdom;2. The Digital Angiographic Reading Center (DARC), New York, New York;3. International Drug Development Institute (IDDI), Louvain-la-Neuve, Belgium;4. Retinal Consultants of Arizona, Phoenix, Arizona;5. University of Southern California, Los Angeles, California;6. Retina Consultants of Texas, Houston, Texas;7. Retina-Vitreous Associates Medical Group, Beverly Hills, California;8. Opthea Limited, Melbourne, Australia |
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| Keywords: | Anti–VEGF-C and D inhibitor Intravitreal injection Neovascular age-related macular degeneration OPT-302 Randomized controlled trial AE" },{" #name" :" keyword" ," $" :{" id" :" kwrd0040" }," $$" :[{" #name" :" text" ," _" :" adverse event AMD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0050" }," $$" :[{" #name" :" text" ," _" :" age-related macular degeneration BCVA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0060" }," $$" :[{" #name" :" text" ," _" :" best-corrected visual acuity CI" },{" #name" :" keyword" ," $" :{" id" :" kwrd0070" }," $$" :[{" #name" :" text" ," _" :" confidence interval CNV" },{" #name" :" keyword" ," $" :{" id" :" kwrd0080" }," $$" :[{" #name" :" text" ," _" :" choroidal neovascularization CST" },{" #name" :" keyword" ," $" :{" id" :" kwrd0090" }," $$" :[{" #name" :" text" ," _" :" central subfield thickness IOP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0100" }," $$" :[{" #name" :" text" ," _" :" intraocular pressure mITT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0110" }," $$" :[{" #name" :" text" ," _" :" modified intent-to-treat nAMD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0120" }," $$" :[{" #name" :" text" ," _" :" neovascular age-related macular degeneration SD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0130" }," $$" :[{" #name" :" text" ," _" :" standard deviation SD-OCT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0140" }," $$" :[{" #name" :" text" ," _" :" spectral-domain OCT VEGF" },{" #name" :" keyword" ," $" :{" id" :" kwrd0dddd145" }," $$" :[{" #name" :" text" ," _" :" vascular endothelial growth factor VEGFR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0150" }," $$" :[{" #name" :" text" ," _" :" VEGF receptor VFQ-25" },{" #name" :" keyword" ," $" :{" id" :" kwrd0160" }," $$" :[{" #name" :" text" ," _" :" 25-item Visual Function Questionnaire |
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