Mendelian Randomization Implicates Bidirectional Association between Myopia and Primary Open-Angle Glaucoma or Intraocular Pressure |
| |
| Affiliation: | 1. Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Republic of Singapore;2. Ophthalmology & Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore, Republic of Singapore;3. Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore;4. Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore;5. Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore;1. Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts;2. Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts;3. Program in Medical and Population Genetics and Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, Massachusetts;4. Tufts University School of Medicine, Boston, Massachusetts;5. Department of Computer Science, University of Toronto, Toronto, Canada;6. Computer Science and Electrical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts;7. Department of Ophthalmology, Yale School of Medicine, New Haven, Connecticut;8. Northern California Retina Vitreous Associates, Mountain View, California;1. Department of Ophthalmology, Zhengda Guangming Eye Group, Yantai Zhengda Guangming Eye Hospital, Yantai, Shandong, China; and Zhengda Guangming International Eye Research Center, Qingdao University, Qingdao, China;2. Department of Nursing, Yantai Yuhuangding Hospital, Yantai, Shandong, China;1. John A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah;2. Medical School, Medical College of Wisconsin, Milwaukee, Wisconsin;3. Loma Linda School of Medicine, Loma Linda, California;4. Division of Epidemiology, Department of Internal Medicine, University of Utah, Salt Lake City, Utah;5. Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin |
| |
| Abstract: | |
| |
| Keywords: | Glaucoma Intraocular pressure Mendelian randomization Myopia CAUSE" },{" #name" :" keyword" ," $" :{" id" :" kwrd0035" }," $$" :[{" #name" :" text" ," _" :" causal analysis using summary effect estimates CI" },{" #name" :" keyword" ," $" :{" id" :" kwrd0045" }," $$" :[{" #name" :" text" ," _" :" confidence interval CREAM" },{" #name" :" keyword" ," $" :{" id" :" kwrd0055" }," $$" :[{" #name" :" text" ," _" :" Consortium for Refractive Error and Myopia GWAS" },{" #name" :" keyword" ," $" :{" id" :" kwrd0065" }," $$" :[{" #name" :" text" ," _" :" genome-wide association study IGGC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0075" }," $$" :[{" #name" :" text" ," _" :" International Glaucoma Genetics Consortium IOP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0085" }," $$" :[{" #name" :" text" ," _" :" intraocular pressure IV" },{" #name" :" keyword" ," $" :{" id" :" kwrd0095" }," $$" :[{" #name" :" text" ," _" :" instrumental variable LDSC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0105" }," $$" :[{" #name" :" text" ," _" :" linkage disequilibrium score regression MR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0115" }," $$" :[{" #name" :" text" ," _" :" Mendelian randomization POAG" },{" #name" :" keyword" ," $" :{" id" :" kwrd0125" }," $$" :[{" #name" :" text" ," _" :" primary open-angle glaucoma RNFL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0135" }," $$" :[{" #name" :" text" ," _" :" retinal nerve fiber layer RSE" },{" #name" :" keyword" ," $" :{" id" :" kwrd0145" }," $$" :[{" #name" :" text" ," _" :" refractive spherical equivalent SE" },{" #name" :" keyword" ," $" :{" id" :" kwrd0155" }," $$" :[{" #name" :" text" ," _" :" standard error SEM" },{" #name" :" keyword" ," $" :{" id" :" kwrd0165" }," $$" :[{" #name" :" text" ," _" :" structural equation modeling SNP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0175" }," $$" :[{" #name" :" text" ," _" :" single nucleotide polymorphism UKB" },{" #name" :" keyword" ," $" :{" id" :" kwrd0185" }," $$" :[{" #name" :" text" ," _" :" UK Biobank |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
