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RECIST标准评价食管癌新辅助化疗疗效的可行性研究
引用本文:朱学庆,张从军,钱勇,陈振东.RECIST标准评价食管癌新辅助化疗疗效的可行性研究[J].安徽医药,2009,13(5):521-523.
作者姓名:朱学庆  张从军  钱勇  陈振东
作者单位:安徽省铜陵市人民医院肿瘤内科,安徽,铜陵,244000;安徽医科大学第一附属医院肿瘤内科,安徽,合肥,230022
基金项目:安徽省自然科学基金重点项目 
摘    要:目的探讨运用RECIST标准评价食管癌新辅助化疗疗效的可行性。方法选择新辅助化疗食管癌患者。根据食管钡餐X线片显示病变长度,将食管病灶分为T1、T2、乃、T4期,CT扫描确定N、M分期。FLP方案化疗2个周期后,按照RECIST标准评价食管癌化疗疗效。结果68例患者中,T1、T2、T3、T4期分别为2、31、24、11例,N0、N1期分别为12、56例。临床分期Ⅲ、Ⅳa及Ⅳb期分别为25、20、23例。化疗2个周期后评价疗效,CR1例,PR27例,SD30例,PD10例,RR为41%。结论RE-CIST标准能够评价食管癌新辅助化疗疗效,食管钡餐X线片显示病灶长度确定食管癌T分期,更适用于临床应用。

关 键 词:食管癌  临床分期  RECIST  新辅助化疗

Feasibility study on evaluation of neoadjuvant chemotherapeutic response of esophageal cancer with RECIST criteria
ZHU Xue-qing,ZHANG Cong-jun,QING Yong,CHEN Zhen-dong.Feasibility study on evaluation of neoadjuvant chemotherapeutic response of esophageal cancer with RECIST criteria[J].Anhui Medical and Pharmaceutical Journal,2009,13(5):521-523.
Authors:ZHU Xue-qing  ZHANG Cong-jun  QING Yong  CHEN Zhen-dong
Institution:ZHU Xue-qing1,ZHANG Cong-jun2,QING Yong2,CHEN Zhen-dong2(1.Department of Oncology,Tongling People\'s Hospital,Tongling 244000,China,2.Department of Oncology,The First Affiliated Hospital of Anhui Medical University,Hefei 230022,China)
Abstract:Aim To assess the feasibility of the response of neoadjuvant chemotherapy in esophageal cancer with RECIST criteria.Methods The esophageal cancer patients with neoadjuvant chemotherapy were selected.According to barium meal X-ray film,the primary lesion lengths in esophagus were divided into T1,T2,T3 and T4.The N and M stage was determined by CT scan.The response was evaluated according to RECIST criteria after 2 cycles of chemotherapy of FLP regimen.Results There were 2 cases for T1,31 cases for T2,24 case...
Keywords:RECIST
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