| VEGF及其受体与肝细胞癌血管生成和抗血管治疗研究进展 |
| |
| 引用本文： | 陈杰,侯恩存. VEGF及其受体与肝细胞癌血管生成和抗血管治疗研究进展[J]. 现代肿瘤医学, 2016, 0(3): 498-502. DOI: 10.3969/j.issn.1672-4992.2016.03.048 |
| |
| 作者姓名： | 陈杰 侯恩存 |
| |
| 作者单位： | 广西中医药大学附属瑞康医院肿瘤科，广西 南宁 530011 |
| |
| 基金项目： | 广西自然科学基金项目(2011GXNSFA018280) |
| |
| 摘 要： | 肝细胞癌(hepatocellular carcinoma，HCC)发生发展与肿瘤血管生成密切相关，而血管内皮生长因子(vascular endothelial growth factor，VEGF)及其受体能直接或间接参与肝癌血管生成，且具有很强的促进作用，在肝癌的发生、发展及预后中扮演着极其重要的角色。近年来，以VEGF及其受体为靶点的肿瘤抗血管治疗是HCC治疗研究的热点。本文复习近十年相关文献，对VEGF及其受体与HCC肿瘤血管生成和HCC抗血管治疗相关研究进展作简要综述。
|
| 关 键 词： | 血管内皮生长因子 血管内皮生长因子受体 肝细胞癌 抗血管治疗 |
Progress of VEGF and its receptors in HCC angiogenesis and antiangiogenesis therapy |
| |
| Chen Jie,Hou Encun. Progress of VEGF and its receptors in HCC angiogenesis and antiangiogenesis therapy[J]. Journal of Modern Oncology, 2016, 0(3): 498-502. DOI: 10.3969/j.issn.1672-4992.2016.03.048 |
| |
| Authors: | Chen Jie Hou Encun |
| |
| Affiliation: | Department of Oncology,Ruikang Hospital Affiliated to Guangxi University of Traditional Chinese Medicine，Guangxi Nanning 530011，China. |
| |
| Abstract: | The development of hepatocellular carcinoma（HCC) is closely related to angiogenesis of tumors，vascular endothelial growth factor（VEGF).Its receptor involves directly or indirectly in angiogenesis of HCC with a strong promoting function and plays very important role on the occurrence，development and prognosis of HCC.In recent years，tumor antiangiogenesis therapy targeted on VEGF and its receptors is a hotspot in HCC treatment.This paper aims to make a review on related research progress of VEGF and its receptors in HCC angiogenesis and antiangiogenesis therapy. |
| |
| Keywords: | vascular endothelial growth factor (VEGF) vascular endothelial growth factor receptor (VEGFR) hepatocellular carcinoma(HCC) antiangiogenesis therapy |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《现代肿瘤医学》浏览原始摘要信息 |
|
点击此处可从《现代肿瘤医学》下载全文 |
