有氧运动对结直肠癌术后辅助化疗患者癌因性疲乏及生活质量的影响

目的:研究有氧运动对结直肠癌术后辅助化疗患者癌因性疲乏及生活质量的影响。方法:对60例结直肠癌术后行第一周期辅助化疗患者，按入院时住院号的奇偶数分为实验组与对照组，每组30例，实验组在接受常规出院健康的指导基础上进行有氧运动干预，对照组仅接受常规的出院康复指导。干预前、后采用Piper疲乏修正量表（revised piper fatigue scale，RPFS）、欧洲癌症治疗与研究组织的生活质量问卷（EORTC-QLQ-C30）对患者的CRF及生活质量进行评定分析。结果:有氧运动干预结束时，收集60例患者资料，结直肠癌患者术后辅助化疗，均有不同程度的癌因性疲乏（cancer-related fatigue，CRF）；两组RPFS评分比较，差异具有统计学意义（P＜0.05）；两组生活质量比较，有氧运动干预后EORTC-QLQ-C30分值明显提高，差异具有统计学意义（P＜0.05）。结论:结直肠癌术后辅助化疗患者普遍存在CRF；对该类患者采用有氧干预，能有效缓解其CRF的程度，并提高生活质量。

Effect of aerobic exercise on cancer related fatigue and quality of life of patients with post-operative adjuvant chemotherapy for colorectal cancer

Objective:To study the effect of aerobic exercise on the cancer fatigue and quality of life in patients with colorectal cancer after chemotherapy. Methods:All 60 cases of colorectal cancer were treated with the first cycle adjuvant chemotherapy,and the number of patients admitted to hospital were divided into experimental group and con-trol group,30 cases in each group. The experimental group received routine health guidance on the basis of aerobic ex-ercise intervention,while the control group received routine rehabilitation guidance. Before the intervention,the quality of life of patients with EORTC - QLQ - C30 and CRF were assessed by revised piper fatigue scale(RPFS),European cancer treatment and research organization. Results:In the end of aerobic exercise intervention,records of 60 patients were collected. The two groups had a significant difference in the quality of life(EORTC - QLQ - C30),and the difference was statistically significant(P < 0. 05). Conclusion:CRF is common in patients with colorectal cancer,and it can effectively relieve the degree of CRF and improve the quality of life.