| 人表皮生长因子受体-2及雌激素受体与乳腺癌的关系 |
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| 引用本文： | 郭奕阳,张金艳. 人表皮生长因子受体-2及雌激素受体与乳腺癌的关系[J]. 现代肿瘤医学, 2016, 0(17): 2802-2805. DOI: 10.3969/j.issn.1672-4992.2016.17.039 |
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| 作者姓名： | 郭奕阳 张金艳 |
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| 作者单位： | 河北医科大学第四医院检验科，河北 石家庄 050011 |
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| 基金项目： | 河北省卫生厅科研基金项目(编号ZL20140109) |
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| 摘 要： | 乳腺癌与人表皮生长因子受体-2及雌激素受体关系密切，这两种受体也是乳腺癌的分类标准和治疗靶点。在大多数乳腺癌患者中，人表皮生长因子受体-2信号途径和雌激素受体信号途径参与了细胞的增生存活过程。而且在乳腺癌病例中，人表皮生长因子受体-2和雌激素受体呈现出一定程度的负相关。这说明这两种受体活化后有一些联系。本文简要综述了人表皮生长因子受体-2和雌激素受体的联系以及这种联系在乳腺癌治疗中的意义。
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| 关 键 词： | 乳腺癌 人表皮生长因子受体-2 雌激素受体 |
The relation of breast cancer with human epidermal growth factor receptor 2 and estrogen receptor |
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| Guo Yiyang,Zhang Jinyan. The relation of breast cancer with human epidermal growth factor receptor 2 and estrogen receptor[J]. Journal of Modern Oncology, 2016, 0(17): 2802-2805. DOI: 10.3969/j.issn.1672-4992.2016.17.039 |
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| Authors: | Guo Yiyang Zhang Jinyan |
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| Affiliation: | Department of Laboratory Medicine，the Fourth Hospital of Hebei Medical University，Hebei Shijiazhuang 050011，China. |
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| Abstract: | Human epidermal growth factor receptor 2 and estrogen receptor were found in breast cancer.Breast canc-er was classified by human epidermal growth factor receptor 2 and estrogen receptor.The estrogen receptor and the hu-man epidermal growth factor receptor 2 signaling pathways are the dominant drivers of cell proliferation and survival in the majority of human breast cancer.There was an inverse correlation between the human epidermal growth factor re-ceptor 2 and the estrogen receptor in many breast cancer cases.There was a correlation between the human epidermal growth factor receptor 2 signaling pathways and the estrogen receptor signaling pathways.We reviewed the correlation and the clinical use of the correlation. |
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| Keywords: | breast cancer human epidermal growth factor receptor 2 estrogen receptor |
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