| 红毛五加镇痛解热作用及毒性的实验观察 |
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| 引用本文： | 邓虹殊,孙士勇,李淑玉.红毛五加镇痛解热作用及毒性的实验观察[J].中国中药杂志,1994,19(1):38-40. |
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| 作者姓名： | 邓虹殊 孙士勇 李淑玉 |
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| 作者单位： | 南方医院 广州 510515,北京医科大学 100083,兰州医学院 730000 |
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| 摘 要： | 实验结果证明,红毛五加醇提物有明显镇痛作用,并能降低家兔正常及蛋白陈致发热体温,但对霍乱菌苗引起的发热体温无影响。红毛五加醇提物的小鼠ipLD50为73.34±7.29g/kg,长期大量po红毛五加醇提物对大鼠血象、肝肾功能无影响。
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| 关 键 词： | 红毛五加 镇痛 解热 毒性 |
| 收稿时间： | 1992/5/15 0:00:00 |
An Experimental Observation on the Analgesic and Antipyretic Effects and Toxicity of Acanthopanax giraldii Harms |
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| Deng Hongzhu;Sun Shiyong;Li Shuyu.An Experimental Observation on the Analgesic and Antipyretic Effects and Toxicity of Acanthopanax giraldii Harms[J].China Journal of Chinese Materia Medica,1994,19(1):38-40. |
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| Authors: | Deng Hongzhu;Sun Shiyong;Li Shuyu |
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| Abstract: | Experimental data indicate that EtOH extract of Acanthopanax giraldii (EAGH) has pronounced analgesic ac-tion and reduces not only high temperature induced by proteinic jelly,but also normal body temperature in rabbits.However no effect was observed On the fever induced by choleraic vaccine in rabbits. The acute ip LD50 of EAGH inmice was 73.34 ±7. 29g/kg(crude drug).In prolonged toxicity test on rats no harmful effects on body weight,blood picture,liver and kidney functions were observed. |
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| Keywords: | Acanthppanax giraldii analgesic action antipyretic action toxicity |
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