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大剂量甲基强的松龙冲击疗法治疗系统性红斑狼疮48例临床分析
引用本文:于华,师清芝,王琪,吴洪燕. 大剂量甲基强的松龙冲击疗法治疗系统性红斑狼疮48例临床分析[J]. 中国医院用药评价与分析, 2001, 1(6): 343-344
作者姓名:于华  师清芝  王琪  吴洪燕
作者单位:1. 哈尔滨医科大学第一临床医学院,哈尔滨市,150001
2. 施维雅药业,哈尔滨市,150001
摘    要:目的观察大剂量甲基强的松龙冲击疗法的临床疗效及与常规激素疗法进行比较.方法对我院1993年~2000年资料较完整的48例系统性红斑狼疮重点在治疗效果上进行分析.结果经采用大剂量甲基强的松龙冲击疗法治疗的36例中,好转31例(86.1%),无效4例(11.1%),死亡1例(2.8%);经常规激素治疗的12例中,好转7例(58.3%),无效2例(16.7%),死亡3例(25%).结论大剂量甲基强的松龙冲击疗法在疗效等方面优于常规激素疗法.

关 键 词:大剂量冲击疗法  甲基强的松龙  常规激素疗法  系统性红斑狼疮  疗效  临床分析
文章编号:2001-06-0343-02
修稿时间:2001-11-29

Clinical Analysis of 48 Cases of SLE Treated With Ictus Treatment of Large Dose Methylprednisolone
YU Hua,SHI Qingzhi,WANG Qi. Clinical Analysis of 48 Cases of SLE Treated With Ictus Treatment of Large Dose Methylprednisolone[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2001, 1(6): 343-344
Authors:YU Hua  SHI Qingzhi  WANG Qi
Abstract:OBJECTIVE:To observe the therapeutic effect of ictus treatment of large dose methylprednisolone on SLE and to compare the effect with that of routine hormonotherapy .METHODS: The therapeutic effects in 48 cases of SLE, admitted to our hospital in 1993-2000, were analysed .RESULTS: Among 36 cases receiving ictus treatment of large dose melhylpred-nisolone, 31 improved (86.1% ), 4 failed(11. 1% ) and 1 died(2.8%); Among 12 cases receiving routine hormonotherapy, 7 improved (58.3% ), 2 failed(16.7%) and 3 died(25%) .CONCLUSION: The ictus treatment of large dose methylprednisolone is superior to routine hormonotherapy in therapeutic effect.
Keywords:ictus treatment of large dose drug  methylprednisolone  routine hormonotherapy  systemic lupis erythematous (SLE)  therapeutic effect  clinical analysis  
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