| 甲状腺激素对大鼠脾淋巴细胞内ACTH的影响 |
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| 引用本文： | 汪保安,窦京涛,汪寅章,陆思珍.甲状腺激素对大鼠脾淋巴细胞内ACTH的影响[J].标记免疫分析与临床,2001,8(2):89-91. |
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| 作者姓名： | 汪保安 窦京涛 汪寅章 陆思珍 |
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| 作者单位： | 解放军总医院内分泌科 |
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| 摘 要： | 本实验通过药物诱发SD大鼠发生甲亢和甲低，研究甲状激素对脾淋巴细胞内免疫反应性ACTH（irACTH)的影响，甲亢组大鼠体重显著低于甲低组和对照组；血清TT3，FT3，TT4，FT4在甲亢组和甲低组间有显著差异；相同细胞数内irACTH量，甲亢组略高于对照组，而甲低组则显著低于另两组，表明甲状腺激素对淋巴细胞内irACTH的合成有正调节作用。
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| 关 键 词： | 甲状腺激素 免疫反应性ACTH 脾淋巴细胞 大鼠 |
| 文章编号： | 1006-1703(2001)02-0089-03 |
| 修稿时间： | 2000年4月19日 |
The Effcet of Thyroid Hormones on Immunoreactive Adrenocorticotropic Hormone in Lymphocytes |
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| WANG Bao-an,DOU Jing-tao,WANG Yin-zhang,et al..The Effcet of Thyroid Hormones on Immunoreactive Adrenocorticotropic Hormone in Lymphocytes[J].Labeled Immunoassays and Clinical Medicine,2001,8(2):89-91. |
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| Authors: | WANG Bao-an DOU Jing-tao WANG Yin-zhang |
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| Abstract: | The effect of thyroid hormones on immunoreactive adrenocorticotropic hormone (irACTH) in lymphocytes, the hyperthyroidism and hypothyroidism rat models were induced by injection of L-T 4 and Methiomazole respectively, and confirmed by body weight and serum thyroid hormones levels. Compared with controls in identical number of cells, irACTH levels of hyperthyroidism group increased slightly and that of hypothyroidism group decreased significantly. This result indicated that thyroid hormones might regulate the synthesis of irACTH in lymphocytes. |
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| Keywords: | Thyroid hormones Lymphocytes irACTH |
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