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Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers |
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| Authors: | Desheng Weng Jeffrey H Penzner Baizheng Song Shigeo Koido Stuart K Calderwood Jianlin Gong |
| Affiliation: | (1) Department of Medicine, Boston University School of Medicine, 650 Albany Street, Boston, MA 02118, USA;(2) Department of Internal Medicine, Jikei University School of Medicine, 163-1 Kashiwa-shita, Kashiwa, Chiba 277-8567, Japan;(3) Molecular and Cellular Radiation Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, 99 Brookline Avenue, Boston, MA 02215, USA |
| Abstract: | IntroductionIt is still uncertain whether metastasis is predominantly an early or late event in tumor progression. The detection of early metastases and cells responsible for the dissemination may therefore have significant clinical implications. |
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