完全腹腔镜全胃切除治疗家族性胃癌与普通胃癌的预后疗效对比

目的 对比完全腹腔镜全胃切除治疗家族性胃癌与普通胃癌的预后疗效。方法 2012年8月—2014年8月选择在我院进行诊治的普通胃癌患者60例作为对照组,同期选择收治的家族性胃癌患者40例作为观察组,都给予腹腔镜辅助下根治性全胃切除术。结果 两组手术时间、术中出血量、术后排气时间对比差异无统计学意义(P＞0.05),但观察组的术后住院时间与淋巴结清扫个数明显多于对照组(P＜0.001)。观察组术后发生并发症如腹腔感染、肺部感染、肠梗阻、手术吻合处出血等情况均明显少于对照组(P＜0.001)。术后1个月进行调查,观察组的吞咽困难、疼痛、焦虑、躯体外观和口干等评分明显高于对照组(P＜0.001)。结论 家族性胃癌具有独特的临床病理特点,相对于普通胃癌,完全腹腔镜全胃切除治疗家族性胃癌需要清扫更多的淋巴结,能造成更多的并发症,对于患者生活质量也有一定的影响。

Comparative prognosis efficacy between total laparoscopic gastrectomy and ordinary gastric cancer for familial gastric cancer

Objective To compare the prognosis efficacy between total laparoscopic gastrectomy and ordinary gastric cancer for familial gastric cancer.Methods The selected 60 patients with ordinary gastric cancer from August 2012 to 2014 in our hospital as the control group,the same period in familial gastric cancer of 40 patients were chosen as control group.All patients were performed by total laparoscopic gastrectomy.Results The operative time,blood loss,postoperative discharge time compared in the two groups were showed no significant differences.However,the postoperative hospital stayed in the observation group and the number of lymph nodes were significantly longer more than the control group(P＜0.001).The postoperative pulmonary infection,intestinal obstruction,abdominal infection,anastomotic leakage,anastomotic bleeding and other complications in the observation group were significantly lower than in the control group(P＜0.001).After the investigation,the dysphagia,pain,anxiety,physical appearance,dry mouth scores in the observation group were significantly higher(P＜0.001).Conclusion Familial gastric cancer has unique clinical and pathological features,Compared to ordinary stomach,the total laparoscopic gastrectomy treatment of familial gastric cancer need more lymph nodes dissection,it can cause more complications,it has some impacts on the quality of life for patients.