| 饮水与肝癌(英文) |
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| 引用本文： | 阮萃才,陈艳华,张振权. 饮水与肝癌(英文)[J]. World journal of gastroenterology : WJG, 1997, 3(1): 47-49. DOI: 10.3748/wjg.v3.i1.47 |
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| 作者姓名： | 阮萃才 陈艳华 张振权 |
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| 作者单位： | 广西肿瘤防治研究所 |
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| 摘 要： | 目的探讨广西肝癌高发区饮用水的诱变效应与肝癌发病的关系．方法应用蚕豆根尖微核技术检测肝癌高发区扶绥县３２份不同饮水类型的饮用水（饮用塘水１３份，塘边井水３份，井水５份，河水６份，自来水５份）的诱变活性研究其微核效应与肝癌的关系．结果３２份不同类型的饮用水中有１２份饮用塘水和２份塘边井水明显诱发蚕豆根尖微核率增高（Ｐ＜００１），平均微核率分别为１５８‰和１１７‰，而井水、河水和自来水所诱发的蚕豆根尖微核率分别为４３‰，３９‰和４２‰，与对照组则无显著差异（Ｐ＞００５），各种不同类型的饮用水所诱发的蚕豆根尖微核效应与当地居民肝癌发病率呈正相关关系（ｒ＝０８６Ｐ＜００５）．结论广西肝癌高发区饮用塘水中存在染色体畸变的物质，肝癌发病率与各种不同类型的饮用水密切相关．摄入水中化学诱变剂可能是导致肝癌高发的重要危险因素之一．
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| 关 键 词： | 肝肿瘤／流行病学 饮用水 水污染 豆科植物 微核试验 |
| 收稿时间： | 1996-08-08 |
Drinking water and liver cancer * |
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| RUAN Cui Cai,CHEN Yan Hua and ZHANG Zhen Quan. Drinking water and liver cancer *[J]. World journal of gastroenterology : WJG, 1997, 3(1): 47-49. DOI: 10.3748/wjg.v3.i1.47 |
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| Authors: | RUAN Cui Cai CHEN Yan Hua ZHANG Zhen Quan |
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| Affiliation: | Cui-Cai Ruan, Yan-Hua Chen, Zhen-Quan Zhang, Department of Chemistry and Mycology, Guangxi Cancer Institute, Nanning 530027, Guangxi Province, China;Cui-Cai Ruan, MD, Associate Professor, Vice Editor in Chief and Director of Chinese Medical Abstracts Oncology, with 68 published papers;Yan-Hua Chen, Assistant Prof and Prof Zhang Zhen Quan, Guangxi Cancer Institute |
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| Abstract: | AIM To study the relationship between mutagenicity of drinking water and incidence of liver cancer in high liver cancer incidence areas in Guangxi. |
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| Keywords: | Drinking water Liver neoplasms legumes Micronucleus tests |
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