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| m6A甲基化修饰结合蛋白YTHDF2在食管癌组织中的表达及其对食管癌细胞增殖和迁移的影响 | |
| 引用本文： | 马琰迪,卢香云,何尚峰,俞雪燕,胡云华,高海霞,陈云昭,禹洁,王文洁,李锋,崔晓宾.m6A甲基化修饰结合蛋白YTHDF2在食管癌组织中的表达及其对食管癌细胞增殖和迁移的影响[J].吉林大学学报(医学版),2022,48(4):962-970. |
| 作者姓名： | 马琰迪 卢香云 何尚峰 俞雪燕 胡云华 高海霞 陈云昭 禹洁 王文洁 李锋 崔晓宾 |
| 作者单位： | 石河子大学医学院病理学系，新疆 石河子 832002 江苏省苏州市高新区人民医院病理科，江苏 苏州 215000 首都医科大学附属北京朝阳医院病理科，北京 100200 南京大学医学院附属鼓楼医院病理科，江苏 南京 210008 |
| 基金项目： | 国家自然科学基金项目(82160542);新疆生产建设兵团科技局重点领域科技攻关计划项目(2020AB022);江苏省苏州市高新区医疗卫生科技计划项目(2018Q004);江苏省苏州市高新区人民医院科学创新基金项目(SGY2020A01);石河子大学科技项目(ZZZC202124) |
| 摘 要： | |
| 关 键 词： | 食管肿瘤 鳞状细胞癌 YTH结构域连接蛋白2 细胞增殖 细胞迁移 |
| 收稿时间： | 2021-11-24 |
Expression of m6A methylation binding protein YTHDF2 in esophageal carcinoma tissue and its effect on proliferation and migration of esophageal carcinoma cells |
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| Yandi MA,Xiangyun LU,Shangfeng HE,Xueyan YU,Yunhua HU,Haixia GAO,Yunzhao CHEN,Jie YU,Wenjie WANG,Feng LI,Xiaobin CUI.Expression of m6A methylation binding protein YTHDF2 in esophageal carcinoma tissue and its effect on proliferation and migration of esophageal carcinoma cells[J].Journal of Jilin University: Med Ed,2022,48(4):962-970. | |
| Authors: | Yandi MA Xiangyun LU Shangfeng HE Xueyan YU Yunhua HU Haixia GAO Yunzhao CHEN Jie YU Wenjie WANG Feng LI Xiaobin CUI |
| Institution: | Department of Pathology, School of Medical Sciences, Shihezi University, Shihezi 832002, China Department of Pathology, Suzhou High Tech Zone People’s Hospital, Suzhou 215000, China Department of Pathology and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China Department of Pathology, Affiliated Nanjing Drum Tower Hospital, School of Medical Sciences, Nanjing University, Nanjing 210008, China |
| Abstract: | Objective To investigate the expression of N6-methyladenosine（m6A） methylation binding protein YTH domain-containing family protein 2 （YTHDF2） in the esophageal squamous cell carcinoma （ESCC） tissue and its effect on the biological behavior of esophageal carcinoma cells，and to clarify its possible mechanism. |
| Keywords: | Esophageal neoplasms Squamous cell carcinoma YTH domain-containing family protein 2 Cell proliferation Cell migration |
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