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嗜酸性粒细胞性肠炎伴复发性急性胰腺炎一例
引用本文:邹龙,王强,吴晰,王志伟,杨爱明. 嗜酸性粒细胞性肠炎伴复发性急性胰腺炎一例[J]. 协和医学杂志, 2022, 13(6): 1100-1104. DOI: 10.12290/xhyxzz.2021-0803
作者姓名:邹龙  王强  吴晰  王志伟  杨爱明
作者单位:1.中国医学科学院北京协和医院病理科,北京 100730
基金项目:北京市重点建设一流专业项目2021zlgc1106
摘    要:本文报道1例具有阿司匹林加重性呼吸系统疾病病史的患者,出现嗜酸性粒细胞性肠炎和复发性急性胰腺炎。此病例具有多系统受累临床特征及嗜酸性粒细胞浸润组织学表现,故临床疑诊为嗜酸性肉芽肿性多血管炎。患者合并出现急性胰腺炎是该疾病非常少见的临床表现;此外,患者存在胰腺假性囊肿,囊肿穿刺引流术后出现迟发性假性动脉瘤出血,经血管造影栓塞治疗后成功止血,术后1年复查病情稳定。该病例的诊断和处理过程复杂,其诊治经验值得临床医师借鉴。

关 键 词:嗜酸性粒细胞性肠炎  急性胰腺炎  阿司匹林加重性呼吸系统疾病  嗜酸性肉芽肿性多血管炎  假性动脉瘤出血
收稿时间:2021-12-27

Eosinophilic Enteritis Accompanied with Recurrent Acute Pancreatitis: A Case Resport
Affiliation:1.Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China2.Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China3.Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
Abstract:This was a patient with a medical history of aspirin-aggravated respiratory disease present with eosinophilic enteritis and recurrent acute pancreatitis. Eosinophilic granulomatosis with polyangiitis was clinically suspected due to the clinical presentation of multiple systems and the histological appearance of eosinophilic infiltrate, but acute pancreatitis was rarely reported in this disease. In addition, the patient developed pancreatic pseudocyst, and delayed pseudoaneurysm hemorrhage occurred after drainage of the pseudocyst. The hemorrhage was successfully treated after angiographic embolization, and the patient remained stable after one year. The case was reported here because both the diagnosis and the management were challenging and worth learning.
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