噪声作业工人血糖水平与噪声性听力损失的关系

目的 探究血糖与性别之间的交互作用对噪声性听力损失(noise-included hearing loss, NIHL)的影响。方法 采用病例对照研究，询问调查噪声作业工人一般资料、职业史、既往史等资料以及职业健康监护资料，进行单因素分析，然后采用logistic回归模型分析NIHL的影响因素，再进行乘法交互作用分析。结果 调查的1 628例噪声作业工人NIHL 616人(37.84%),NIHL的危险因素有血糖偏高(OR=1.960,95%CI:1.345～2.855)、男性(OR=4.346,95%CI:2.866～6.590)、高环境噪声强度(OR=1.036,95%CI:1.016～1.056)、单核细胞计数偏高(OR=8.522,95%CI:3.054～23.776)、血小板偏低(OR=0.997,95%CI:0.994～0.999)。血糖偏高人员的NIHL风险是血糖正常的1.960倍(P<0.01),男性NIHL的风险是女性的4.346倍(P<0.01),环境噪声强度每增加一个单位，NIHL风险提高1.036倍。血糖偏高与男性对NIHL的加法交互作用有统计学意义...

Relationship between blood glucose level and noise-induced hearing loss in noise-exposed workers

Objective To investigate the effect of interaction between blood glucose and gender on noise-induced hearing loss (NIHL). Methods A case-control study was conducted to inquire and investigate the general information, occupational history, past history and occupational health monitoring data of workers exposed to noise. Univariate analysis was performed. Logistic regression model was used to analyze the factors influencing NIHL, and then multiplicative interaction analysis was conducted. Results Among 1,628 noise-exposed workers surveyed, 616 (37.84%) suffered from NIHL,The risk factors for NIHL were high blood glucose (OR=1.960, 95%CI:1.345-2.855), male (OR=4.346, 95%CI:2.866-6.590), high environmental noise intensity (OR=1.036, 95%CI:1.016-1.056), high monocyte count (OR=8.522, 95%CI:3.054-23.776) and low platelet count (OR=0.997, 95%CI:0.994-0.999). The risk of NIHL in workers with high blood glucose was 1.960 times that of normal blood glucose (P<0.01), and the risk of NIHL in males was 4.346 times that of females (P<0.01). The risk of NIHL increased 1.036 times for each unit increase in the intensity of environmental noise. The additive interaction between high blood glucose and male on NIHL was statistically significant, and the values of odds ratio and synergy index were 8.962 and 2.123, respectively. Conclusion It is necessary to build fasting blood glucose examination into routine examination items of thenoise-exposed workers, strengthen the surveillance on blood glucose level of male noise-exposed workers, screen out workers with high blood glucose and give certain control and intervention, and transfer out of their post if necessary.