2002-2014年南通市肿瘤医院胃癌住院患者生存率分析

目的:对南通市肿瘤医院2002-2014年以医院为基础的肿瘤登记胃癌病例作生存率分析，为综合评估胃癌患者预后提供依据。方法:采用主动随访与被动随访相结合的方法，对癌症登记数据库中来自启东、海门籍的胃癌住院患者进行生存结局的随访。用寿命表法计算观察生存率，并采用SPSS 26软件作生存率比较分析，Wilcoxon统计量Gehan值评估差异的显著性。结果:启东、海门籍胃癌患者428例，失访13例（3.04%），获得癌症生存结局信息者为415例（随访率为96.96%），其中男性278例，女性137例，首次入院平均年龄为61.86±11.99岁，60岁以上老年人共计256例，占59.81%。患者的1年、3年、5年及10年观察生存率分别为51.08%、27.80%、21.62%及18.06%。除1年生存率外，男性2~10年生存率均低于女性生存率，但差异无统计学意义（Wilcoxon 统计量Gehan=0.085，P=0.770）。0~39岁组、40~49岁组、50~59岁组、60~69岁组及≥70岁组的5年总观察生存率分别为33.89%、19.68%、25.23%、23.33%及16.19%,差异无统计学意义。启东籍胃癌患者1~5年观察生存率略高于海门籍患者，而5年以上观察生存率则稍低于海门籍患者，但两组间比较差异无统计学意义（Wilcoxon统计量Gehan=0.317，P=0.573）。结论:胃癌患者生存率的性别差异、年龄别差异及地区差异不显著。与发达国家或地区相比，胃癌的总体生存率有待提高。

Analysis on stomach cancer survival of inpatients from 2002 to 2014 in Nantong Tumor Hospital

Objective:To analyze survival rates of stomach cancer patients from hospital-based cancer registration 2002-2014 in Nantong Tumor Hospital.Methods:Active and passive follow-up methods were used to obtain the information on status of surviving for patients from Qidong city and Haimen city.Survival probability was estimated using the life-table method with SPSS software,and comparison of significant differences in survival rates was tested by Wilcoxon(Gehan).Results:The outcomes of 415 patients were identified in the follow-up for 428 cases from Qidong and Haimen,with a follow-up rate of 96.96%,and a rate of lost to follow-up of 3.04%(13 cases).The series consists of 278 male patients and 137 female patients,the average age of the first-hospitalization was 61.86±11.99 years old.The most commonly affected ages were 60 years old,accounting for 59.81%(256 cases).The 1-,3-,5- and 10-year observed survival(OS) rate were 51.08%,27.80%,21.62% and 18.06%,respectively.Females experienced better survival than males' for the 2~10 year OS rates,but did not for the 1-year OS(Gehan=0.085，P=0.770).The 5-year OS rates of stomach cancer at age groups of 0~39,40~49,50~59,60~69,70+ years were 33.89%,19.68%,25.23%,23.33% and 16.19%,respectively,with no significant differences.Patients from Qidong seem to have experienced better survival than those patients from Haimen for the 1~5 year OS rates，while the 6~10 year OS rates seem little higher in patients from Haimen,but no significant differences were found(P=0.573)．Conclusion:There were no real differences in the survival rates of stomach cancer patients between genders,age groups and regions.Compared with developed countries or regions,the overall survival rate of stomach cancer needs to be improved.