胶质母细胞瘤诊疗研究进展

胶质母细胞瘤是最常见的原发性颅内恶性肿瘤。尽管在过去的几十年里进行了大量的研究，胶质母细胞瘤的预后仍然很差。近年来随着多组学等研究在胶质母细胞瘤中的应用，加深了人们对胶质母细胞瘤的认识，主要体现在诊断上对其分类进行了重新修订。治疗上，在原有的手术和放化疗等标准治疗基础上发展了靶向治疗、免疫治疗和电场治疗等新型治疗方法。本文对胶质母细胞瘤近年来在诊疗中取得的最新进展进行简要述评。

Research Progress of Diagnosis and Treatment of Glioblastoma

Glioblastoma is the most common primary malignant brain tumor. Despite large-scale researches have been carried out, the prognosis of glioblastoma is still not significantly improved. In recent years, with the application of multi-omics studies in glioblastoma, the understanding of glioblastoma has been deepened. The classification of glioblastoma has been revised; moreover, new therapeutic methods such as targeted therapy, immunotherapy and tumor treating fields have been developed on the basis of the standard therapy. This article reviews the recent progress in the diagnosis and treatment of glioblastoma.