脑出血患者并发肺部感染的多因素分析

目的 探讨脑出血患者肺部感染发病状况、影响因素及相关干预措施。方法 选择2016年1月—2020年11月合肥市第三人民医院住院治疗的脑出血患者207例作为研究对象。根据患者住院期间是否出现肺部感染分为肺部感染组(A组，91例)和非感染组(B组，116例)。结合患者人口学资料、病史、病情探讨脑出血并发肺部感染的影响因素。结果 脑出血患者出现肺部感染占比43.96%(91/207)。非条件二分类logistic回归分析显示年龄≥65岁(OR=1.102,95%CI:1.006～2.135)、COPD病史(OR=2.679,95%CI:1.085～6.678)、糖尿病史(OR=3.175,95%CI:2.170～4.156)、格拉斯哥昏迷评分(GCS)≤8分(OR=4.500,95%CI:3.189～5.865)、手术治疗(OR=8.282,95%CI:1.182～31.483)、低蛋白血症(OR=3.864,95%CI:1.170～6.696)是脑出血合并肺部感染的独立危险因素。结论 脑出血患者肺部感染的发生率较高，老年患者、合并糖尿病、COPD病史、GCS评分较低、手术治疗及低蛋白血症等...

Multivariate analysis of pulmonary infection in patients with cerebral haemorrhage

  Objective   To investigate the incidence, influencing factors and related interventions of pulmonary infection in patients with cerebral haemorrhage.  Methods  A total of 207 patients with intracerebral haemorrhage who were admitted in our hospital from January 2016 to November 2020 were selected as the research objects.All patients were divided into the pulmonary infection group (group A, n=91) and non-pulmonary infection group (group B, n=116).To explore the influencing factors of cerebral haemorrhage complicated with pulmonary infection, patient demographic data, medical history and condition were analysed.  Results   The proportion of pulmonary infection in patients with cerebral haemorrhage was 43.96%(91/207).Unconditional binary logistic regression analysis showed that age ≥65 years (OR=1.102, 95%CI: 1.006-2.135), COPD (OR=2.679, 95%CI: 1.085-6.678), diabetes (OR=3.175, 95%CI: 2.170-4.156), GCS≤8(OR=4.500, 95%CI: 3.189-5.865), surgical treatment (OR=8.282, 95%CI: 1.182-31.483) and hypoproteinaemia (OR=3.864, 95%CI: 1.170-6.696) were independent risk factors for cerebral haemorrhage complicated with pulmonary infection.  Conclusion   Patients with cerebral haemorrhage have a higher incidence of lung infections.Age≥65 years, diabetes, COPD, low GCS score, surgical treatment and hypoproteinaemia can independently affect the occurrence of pulmonary infection in patients with cerebral haemorrhage.Therefore, we should strengthen the intervention according to the relevant influencing factors to reduce the occurrence of pulmonary infection and reduce the mortality rate.