电针联合氟西汀对卒中后抑郁症患者抑郁状态及神经功能的影响

目的观察电针联合氟西汀对卒中后抑郁症（PSD）患者抑郁状态及神经功能的影响。方法将95例PSD患者随机分为A、B、C三组,分别采用电针、氟西汀、电针联合氟西汀治疗。治疗前后根据哈密顿抑郁量表（HAMD）、神经功能缺损量表及副反应量表（TESS）评分,评定其抑郁程度、神经功能缺损程度及不良反应。结果治疗6周后,三组治疗前后组内及治疗后组间HAMD评分、神经功能缺损评分、TESS评分比较均有统计学差异（P均〈0.05）,其中C组优于A组及B组（P均〈0.05）。结论电针联合氟西汀能更好地改善PSD患者的抑郁状态,促进其神经功能恢复,且不良反应少,值得临床应用。

Effects of electric-acupuncture and fluoxetine on depression and neurological function of post-stroke depression patients

Objective To evaluate the effects of electric-acupuncture and fluoxetine on depression and neurological function of post-stroke depression（PSD） patients.Methods A total of 95 patients with PSD were randomly divided into the group A,B and C,they were treated with electric-acupuncture,medicine,and electric-acupuncture combined with medicine respectively.The degree of depression and neurological function defect,side-effects were evaluated by hamilton depression scale（HAMD）,the clinical neurological function defect scale and the treatment emergent symptom scale（TESS） before and after treatment.Results After treatment for 6 weeks,HAMD scores,the clinical neurological function defect scale and TESS scores were significantly different in 3 groups（P0.05）,which in the group C was much better than those in group A and B（P0.05）.Conclusion Electric-acupuncture combined with fluoxetine could regulate depression and improve neurological function and reduce side effects of medicine in treating PSD patients.It is deserved to be applied to clinical use.