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乙肝疫苗接种无(低)应答原因及相应对策研究进展
引用本文:肖士海,刘连庚.乙肝疫苗接种无(低)应答原因及相应对策研究进展[J].中国国境卫生检疫杂志,2011(1):69-71.
作者姓名:肖士海  刘连庚
作者单位:盐城出入境检验检疫局保健中心;盐城市中医院;
摘    要:本文总结了人体接种乙肝疫苗后,接种无(低)应答产生的原因,主要包括人体机体本身的因素,低水平乙肝(HBV)感染,接种部位、途径、接种次数,下淋巴细胞和细胞因子水平,遗传因素,乙肝的S基因变异,疾病因素,疫苗改造等;并就目前提高乙肝疫苗无(低)应答者免疫应答率的研究情况做一综述。

关 键 词:乙肝疫苗  接种  应答  进展

Research progress of non(low)-response cause to HB vaccine and corresponding countermeasures
XIAO Shi-hai,LIU Lian-geng Yancheng Inspection Quarantine Bureau,Yancheng,Jiangsu ,Chian.Research progress of non(low)-response cause to HB vaccine and corresponding countermeasures[J].Chinese Journal of Frontier Health and Quarantine,2011(1):69-71.
Authors:XIAO Shi-hai  LIU Lian-geng Yancheng Inspection Quarantine Bureau  Yancheng  Jiangsu  Chian
Institution:XIAO Shi-hai*,LIU Lian-geng *Yancheng Inspection Quarantine Bureau,Yancheng,Jiangsu 224002,Chian
Abstract:This paper summarizes these no(low) responding causes,after the human body vaccination HepB,including human body itself factors,low level hepatitis B virus(HBV) infection,vaccination site,approach,vaccination times,T lymphocytes and cytokines level,genetic factors,hepatitis B S genetic variations,disease factors,the vaccine reform,etc;and summarizing the research situation of improving immune response rates of the no(low) responders now.
Keywords:Hepatitis B  vaccine  Inoculation  Response  Progress  
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