Epidermolysis bullosa acquisita in childhood |
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Authors: | John C Su George A Varigos John Dowling |
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Institution: | Department of Dermatology, Royal Children's Hospital, Parkville;Department of Pathology, Alfred Hospital, Prahran, Victoria, Australia |
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Abstract: | This case report of an 11-year-old girl describes a juvenile form of epidermolysis bullosa acquisita, an autoimmune disease of IgG antibodies to basement membrane type 7 collagen. Our case illustrates an unusually severe, acute inflammatory presentation of this condition with prominent mucosal and constitutional features requiring admission to a paediatric burns unit. The treatment consisted of supportive topical and systemic agents, prednisolone and dapsone. She responded to dapsone alone and the course of the illness was uneventful. |
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Keywords: | autoimmune bullous disease immuno-bullous disease paediatric |
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