Tuberculosis screening after detection of a case in a paediatric haemato-oncology unit in a low prevalence country |
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| Affiliation: | 1. Paediatric Infectious Diseases Unit, Department of Paediatrics, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Spain;2. Instituto de Investigación Hospital 12 de Octubre (imas12), Spain;3. Paediatric Infectious Diseases Unit, Department of Paediatrics, Hospital Universitario La Paz, Madrid, Spain;4. Paediatric Haemato-Oncology Unit, Department of Paediatrics, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Spain;5. Microbiology Department, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Spain;6. Paediatric Radiology Unit, Hospital Universitario 12 de Octubre, Universidad Complutense de Madrid, Spain |
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| Abstract: | BackgroundThere are no guidelines to screen haemato-oncologic children when a tuberculosis (TB) outbreak is suspected.MethodsAfter exposition to an adult with active TB, children exposed from a haemato-oncology unit were screened according to immunosuppression status and time of exposure. Until an evaluation after 8–12 weeks from last exposure, isoniazid was indicated to those with negative initial work-up.ResultsAfter 210 interventions, we detected a case of pulmonary TB, and another with latent TB infection. Pulmonary findings and treatment approach were challenging in some patients.ConclusionsThe TB screening of oncologic children required a multidisciplinary approach, and clinicians managed challenging situations. |
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| Keywords: | Tuberculosis Haemato-oncology Paediatrics Screening Tuberculosis Hematooncología Pacientes pediátricos Cribado |
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