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Tryptophan-kynurenine profile in pediatric autoimmune hepatitis |
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| Authors: | Lytton Simon D. Osiecki Marcin MałgorzataWoźniak Cukrowska Bożena Wierzbicka Aldona Goliszek Maria Socha Piotr Janczyk Wojciech Dayanakli Dilek Abendroth Dieter Kramp Sabine Fechner Kai Scheper Thomas Mahler Michael Bentow Chelsea Bogdanos Dimietrios Fuchs Dietmar Woynarowski Marek |
| Affiliation: | 1.SeraDiaLogistics, Benediktenwandstr 7, 81545, Munich, Germany ;2.Children’s Memorial Health Institute, Warsaw, Poland ;3.Zentrum für Chirurgie Universitätsklinikum Universität Ulm, Parkstr 11, 89073, ULM, Germany ;4.Division of Biological Chemistry, Biocenter Innsbruck Medical University, Center for Chemistry and Biomedicine, Innrain 80, 4th Floor, Room M04-313, A-6020, Innsbruck, Austria ;5.Euroimmun AG, Seekamp 31, D-23560, Lübeck, Germany ;6.Department of Rheumatology and Clinical Immunology, University General Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, Viopolis, 40500, Larissa, Greece ;7.Inova Diagnostics, 9900 Old Grove Road, San Diego, CA, 92131, USA ; |
| Abstract: | Immunologic Research - The impairment of regulatory T cells (Tregs) is a characteristic feature of autoimmune hepatitis (AIH), and the degradation of tryptophan (Trp) to kynurenine (Kyn), by gamma... |
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