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Prevalencia y factores asociados con la presencia de criterios PIMDINAC en pacientes VIH de edad avanzada
Affiliation:1. Servicio de Farmacia, Hospital de Valme, Área de Gestión Sanitaria Sur de Sevilla, Sevilla, España;2. Servicio de Farmacia, Hospital Universitario Virgen del Rocío, Sevilla, España;3. Servicio de Farmacia, Hospital Universitario Virgen Macarena, Sevilla, España;4. Facultad de Farmacia, Universidad de Sevilla, Sevilla, España
Abstract:IntroductionAging of people living with HIV could be related to potentially inappropriate medication prescriptions, drugs interactions and lack of drugs adherence. PIMDINAC criteria seek to jointly analyze these problems. The objective of this study is to determine the prevalence of PIMDINAC criteria in an elderly HIV population.MethodsObservational, cross-sectional, multicenter study that included patients older than 65 years in pharmacotherapeutic follow-up between February-April 2020. The main endpoint was the percentage of PIMDINAC criteria identified in the study population.ResultsForty-seven patientes were included, identifying total PIMDINAC in 12.5%. Non-adherence to concomitant treatment was detected in 65.6% of patients, potentially inappropriate medication in 48.9% and drugs interactions in 25.2%. The number of concomitant drugs and polypharmacy were associated with a higher appearance of PIMDINAC criteria.ConclusionThe prevalence of PIMDINAC criteria in elderly HIV patients is high.
Keywords:Aging  HIV  Drugs interactions  Potentially inappropriate medication  Adherence  Polypharmacy
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