化痰祛瘀汤治疗痰瘀阻滞型高脂血症临床观察

目的观察化痰祛瘀汤治疗高脂血症(痰瘀阻滞型)的临床疗效和安全性。方法将140例患者随机分为2组,各70例。治疗组口服化痰祛瘀汤治疗,对照组口服多烯康胶丸治疗。2组均1个月为1个疗程。观察2组疗效、治疗前后症状积分及血脂各项指标的变化。结果治疗组总有效率91.43%,对照组总有效率72.86%,2组总有效率比较有显著性差异(P<0.05)。治疗组治疗后总胆固醇、甘油三酯、低密度脂蛋白和中医证候积分有明显降低(P<0.05),高密度脂蛋白有明显升高(P<0.05),且治疗组降低总胆固醇、甘油三酯和升高高密度脂蛋白的疗效与对照组比较有显著性差异(P<0.05),且临床未发现不良反应。结论化痰祛瘀汤具有化痰降浊、活血祛瘀之效,有明显的调血脂作用,改善临床症状显著,且无毒副作用,值得临床推广使用。

Clinical observation of Huatanquyu decoction on hyperlipemia based on differentiation of splegm and blood stagnace

Objective To observe the clinical effect and safety of Huatanquyu decoction on hyperlipemia based on the differentiation of splegm and blood stagnace. Methods 140 patients were randomly divided into the treatment group (n=70), which was administreted Huatan quyu decoction and the control group (n=70) which was given epanol pill. One month was a treatment course in the both groups. The clinical curative effective rate, symptoms scores and various indexes of blood-lipid were observed before and after treatment. Results The total effective rate was 91.43% in treatment group, and 72.86% in control group. There was a significant difference between the two groups (P<0.05). Compared with the control group, patients in the treatment group, the level of cholesterol, triglyceride, low density lipoprotein and the symptom scores significantly reduced after treatment (P<0.05), and the level of high density lipoprote significantly increased (P<0.05). There was no clinical adverse reaction observed. Conclusion Huatanquyu decoction can regulate blood-lipid, improve clinical symptoms and has no toxic reaction.